Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1156874 | 0.78 | IFNAR1 (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1057367 | 0.78 | IFNAR1 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2232580 | 0.78 | HDAC3 (0.45) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6293960 | 0.78 | IFNAR1 (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL17058596 | 0.78 | IFNAR1 (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5385179 | 0.78 | HDAC3 (0.42) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3077714 | 0.76 | MEN1 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6057233 | 0.75 | POLB (0.57) | IFNAR1ALDH1A1LMNANPY1RMAPK1 | |
| SCHEMBL1493101 | 0.75 | ALDH1A1 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8038665 | 0.75 | IFNAR1 (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177519-B1 | TETRAZOYLOXIME DERIVATIVE AND PLANT DISEASE CONTROL AGENT | NIPPON SODA CO (JP) | 2015-05-27 | — | — | EP | disclosed |
| US-9029552-B2 | Tetrazoyloxime derivative and plant disease control agent | NIPPON SODA CO., LTD. (JP) | 2015-05-12 | — | — | US | disclosed |
| US-20140005385-A1 | TETRAZOYLOXIME DERIVATIVE AND PLANT DISEASE CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2014-01-02 | — | — | US | disclosed |
| EP-2669282-A1 | Tetrazoyloxime derivative and plant disease control agent | NIPPON SODA CO., LTD. (JP) | 2013-12-04 | — | — | EP | disclosed |
| US-20110209699-A1 | COMBINATION OF DEHYDROEPIANDROSTERONE OR DEHYDROEPIANDROSTERONE-SULFATE WITH A LIPOXYGENASE INHIBITOR FOR TREATMENT OF ASTHMA OR CHRONIC OBSTRUCTIVE PULMONARY DISEASE | EPIGENESIS PHARMACEUTICALS, LLC | 2011-09-01 | — | — | US | disclosed |
| US-20100137594-A1 | TETRAZOYLOXIME DERIVATIVE AND PLANT DISEASE CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
| EP-2177519-A1 | TETRAZOYLOXIME DERIVATIVE AND PLANT DISEASE CONTROL AGENT | Nippon Soda Co., Ltd. (JP) | 2010-04-21 | — | — | EP | disclosed |
| EP-1954320-A2 | COMPOSITIONS COMPRISING LIPOXYGENASE INHIBITORS AND CYCLODEXTRIN | Baxter International Inc. (US) | 2008-08-13 | — | — | EP | disclosed |
| EP-1954245-A2 | COMPOSITIONS OF LIPOXYGENASE INHIBITORS | Baxter International Inc. (US) | 2008-08-13 | — | — | EP | disclosed |
| US-20070134341-A1 | COMPOSITIONS OF LIPOXYGENASE INHIBITORS | BAXTER INTERNATIONAL INC. | 2007-06-14 | — | — | US | disclosed |
| EP-0388429-A1 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-09-26 | — | — | EP | disclosed |
| WO-1989012636-A1 | TRICYCLIC LIPOXYGENASE INHIBITING COMPOUNDS, COMPOSITIONS, METHODS OF USE | ABBOTT LABORATORIES (US) | 1989-12-28 | — | — | WO | disclosed |
| EP-0346939-A1 | Tricyclic lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1989-12-20 | — | — | EP | disclosed |
| US-4873259-A | Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1989-10-10 | — | — | US | disclosed |
| EP-0320628-A1 | Substituted furan compounds which are useful in inhibiting lipoxygenase enzymes, particularly 5-lipoxygenase | ABBOTT LABORATORIES (US) | 1989-06-21 | — | — | EP | disclosed |
| WO-1989004299-A1 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1989-05-18 | — | — | WO | disclosed |
| US-4822811-A | Carbazole lipoxygenase inhibiting compounds, compositions and use | ABBOTT LABORATORIES (US) | 1989-04-18 | — | — | US | disclosed |
| US-4822809-A | ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1989-04-18 | — | — | US | disclosed |
| US-4769387-A | Dibenzofuran lipoxygenase inhibiting compounds, compositions and use | ABBOTT LABORATORIES (US) | 1988-09-06 | — | — | US | disclosed |
| EP-0279263-A2 | Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1988-08-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140005385-A1 | TETRAZOYLOXIME DERIVATIVE AND PLANT DISEASE CONTROL AGENT | PAOX, BROX, TTI2 | HDAC3 1036/4885HDAC4 278/4885HDAC1 699/4885 |
| US-20070134341-A1 | COMPOSITIONS OF LIPOXYGENASE INHIBITORS | ALOX5, ALOX15B, ALOX15 | HDAC3 4359/4885HDAC4 3735/4885HDAC1 2955/4885 |
| US-20110209699-A1 | COMBINATION OF DEHYDROEPIANDROSTERONE OR DEHYDROEPIANDROSTERONE-SULFATE WITH A LIPOXYGENASE INHIBITOR FOR TREATMENT OF ASTHMA OR CHRONIC OBSTRUCTIVE PULMONARY DISEASE | HSD11B2, CYP17A1, ALOX5 | HDAC3 4287/4885HDAC4 3554/4885HDAC1 2625/4885 |
| US-20100137594-A1 | TETRAZOYLOXIME DERIVATIVE AND PLANT DISEASE CONTROL AGENT | PAOX, H1-10, HAX1 | HDAC3 747/4885HDAC4 771/4885HDAC1 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.