Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11347459 | 0.80 | MEN1 (0.46) | CA12CA9MEN1TSHRKMT2A | |
| SCHEMBL11353531 | 0.80 | MEN1 (0.46) | CA12CA9MEN1TSHRKMT2A | |
| SCHEMBL197721 | 0.76 | GAA (0.68) | CA12CA9MEN1TSHRKMT2A | |
| SCHEMBL197333 | 0.76 | GAA (0.68) | CA12CA9MEN1TSHRKMT2A | |
| SCHEMBL11348810 | 0.70 | GSTO1 (0.44) | CA12CA9MEN1TSHRKMT2A | |
| SCHEMBL3116881 | 0.69 | CNR1 (0.56) | CA12CA9MEN1TSHRKMT2A | |
| SCHEMBL11345142 | 0.69 | FABP4 (0.49) | CA12CA9MEN1TSHRKMT2A | |
| SCHEMBL5506453 | 0.69 | FABP4 (0.49) | CA12CA9MEN1TSHRKMT2A | |
| SCHEMBL6836177 | 0.69 | ACLY (0.61) | CA12CA9MEN1TSHRKMT2A | |
| SCHEMBL9577219 | 0.68 | GAA (0.73) | MEN1TSHRKMT2ATP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001051-A2 | Derivatives of benzenesulfonamide, method for their preparation and pharmaceutical compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-03-21 | — | — | EP | disclosed |