Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.68 |
| ▸ | CES1 | P23141 | 3/20 | 0.68 |
| ▸ | MAOB | P27338 | 5/20 | 0.56 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29372550 | 1.00 | CES2 (0.68) | CES2CES1MAOBSNCAL3MBTL1 | |
| Acetonitrile SCHEMBL27854605 | 0.90 | CES2 (0.57) | CES2CES1MAOBSNCAL3MBTL1 | |
| SCHEMBL7777968 | 0.83 | CES2 (0.76) | CES2CES1MAOBSNCAL3MBTL1 | |
| SCHEMBL5210142 | 0.82 | CES2 (0.52) | CES2CES1MAOBKMT2AMAPK14 | |
| SCHEMBL5750296 | 0.82 | CES2 (0.52) | CES2CES1MAOBSNCAMAOA | |
| SCHEMBL364307 | 0.82 | CES2 (0.68) | CES2CES1MAOBMAOA | |
| SCHEMBL29766689 | 0.82 | CES2 (0.68) | CES2CES1MAOBMAOA | |
| SCHEMBL8070666 | 0.81 | CES2 (1.00) | CES2CES1SNCAL3MBTL1 | |
| SCHEMBL18242037 | 0.81 | CES2 (0.60) | CES2CES1MAOBSNCAL3MBTL1 | |
| SCHEMBL13291390 | 0.81 | CES2 (0.74) | CES2CES1SNCAL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 739 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114671737-B | Preparation method of posaconazole main ring intermediate | 张家口市格瑞高新技术有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-115073276-A | Preparation and control method of posaconazole main ring impurity | 济南大学 | 2022-09-20 | — | — | CN | claimed |
| CN-114671737-A | Preparation method of posaconazole main ring intermediate | 张家口市格瑞高新技术有限公司 | 2022-06-28 | — | — | CN | claimed |
| CN-111606848-A | Preparation method of fluorodiphenyl substituted pyridine compound | 广西民族大学 | 2020-09-01 | — | — | CN | claimed |
| US-8952083-B2 | Fluorocopolymer composition and its production process | ASAHI GLASS COMPANY, LIMITED (JP) | 2015-02-10 | — | — | US | claimed |
| US-20040158064-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | BLACK LAWRENCE A (US) | 2004-08-12 | — | — | US | claimed |
| US-20030225276-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | BLACK LAWRENCE A (US) | 2003-12-04 | — | — | US | claimed |
| US-20020028938-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | BLACK LAWRENCE A (US) | 2002-03-07 | — | — | US | claimed |
| US-20020013318-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | BLACK LAWRENCE A (US) | 2002-01-31 | — | — | US | claimed |
| EP-1124804-A1 | PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-08-22 | — | — | EP | claimed |
| WO-1999010331-A1 | ARYLPYRIDAZINONES AS PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 1999-03-04 | — | — | WO | claimed |
| EP-0734369-B1 | PROCESS FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF ANTIFUNGAL AGENTS | SCHERING CORP (US) | 1998-11-18 | — | — | EP | claimed |
| EP-0536512-B1 | A method and intermediates for the preparation of 6-fluorobenzisothiazoles | HOECHST MARION ROUSSEL INC (US) | 1997-11-05 | — | — | EP | claimed |
| EP-0734369-A1 | PROCESS FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF ANTIFUNGAL AGENTS | SCHERING CORPORATION (US) | 1996-10-02 | — | — | EP | claimed |
| EP-0694519-A1 | Process for the preparation of 2,4-difluoroacetophenone | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-31 | — | — | EP | claimed |
| WO-1995016658-A1 | PROCESS FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF ANTIFUNGAL AGENTS | SCHERING CORPORATION (US) | 1995-06-22 | — | — | WO | claimed |
| US-5349099-A | Process for preparing intermediates for the synthesis of antifungal agents | SCHERING CORPORATION (US) | 1994-09-20 | — | — | US | claimed |
| EP-0536512-A1 | A method and intermediates for the preparation of 6-fluorobenzisothiazoles | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-04-14 | — | — | EP | claimed |
| EP-0243000-B1 | POLYCYANOARYL ETHER, METHOD FOR PREPARING THE SAME AND USES THEREOF | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-10-03 | — | — | EP | claimed |
| EP-0243000-A1 | Polycyanoaryl ether, method for preparing the same and uses thereof | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1987-10-28 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040158064-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | PTGS1, PTGIS, PTGS2 | CES2 2785/4885CES1 327/4885MAOB 455/4885 |
| US-20020028938-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | PTGS1, PTGIS, PTGS2 | CES2 2722/4885CES1 317/4885MAOB 479/4885 |
| US-20030225276-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | PTGS1, PTGIS, PTGS2 | CES2 2722/4885CES1 317/4885MAOB 479/4885 |
| US-20020013318-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | PTGS1, PTGIS, PTGS2 | CES2 2722/4885CES1 317/4885MAOB 479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.