Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 18/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19178469 | 0.84 | BCHE (0.57) | PTPN1BCHE | |
| SCHEMBL12902907 | 0.83 | BCHE (0.54) | BCHE | |
| SCHEMBL12411490 | 0.81 | BCHE (0.59) | PTPN1BCHE | |
| SCHEMBL12702983 | 0.81 | BCHE (0.59) | PTPN1BCHE | |
| SCHEMBL12942000 | 0.81 | BCHE (0.59) | PTPN1BCHE | |
| SCHEMBL12411488 | 0.81 | BCHE (0.59) | PTPN1BCHE | |
| SCHEMBL19903720 | 0.80 | SERPINE1 (0.55) | PTPN1BCHE | |
| SCHEMBL12258546 | 0.80 | BCHE (0.58) | BCHE | |
| SCHEMBL2395027 | 0.80 | BCHE (0.58) | BCHE | |
| SCHEMBL2395025 | 0.80 | BCHE (0.58) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2665730-B1 | COMPOUNDS WITH SUPER-ASPIRIN EFFECTS | THE PROVOST FELLOWS FOUND SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIV T (IE) | 2019-07-24 | — | — | EP | disclosed |
| US-9670223-B2 | Compounds with super-aspirin effects | SOLVOTRIN THERAPEUTICS LTD. (IE) | 2017-06-06 | — | — | US | disclosed |
| EP-2222681-B1 | EFFICIENT ASPIRIN PRODRUGS | PROVOST FELLOWS & SCHOLARS COLLEGE OF THE HOLY UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2016-02-17 | — | — | EP | disclosed |
| US-20150291615-A1 | COMPOUNDS WITH SUPER-ASPIRIN EFFECTS | SOLVOTRIN THERAPEUTICS LTD (IE) | 2015-10-15 | — | — | US | disclosed |
| US-20140024681-A1 | COMPOUNDS WITH SUPER-ASPIRIN EFFECTS | The Provost,Fellowws, Foudation Scholars, and the Other Members of Board, of the College of the Holy (IE) | 2014-01-23 | — | — | US | disclosed |
| EP-2665730-A1 | COMPOUNDS WITH SUPER-ASPIRIN EFFECTS | The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of the Holy & Undiv. Trinity of Queen Elizabeth near Dublin (IE) | 2013-11-27 | — | — | EP | disclosed |
| US-8486974-B2 | Efficient aspirin prodrugs | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH (IE) | 2013-07-16 | — | — | US | disclosed |
| WO-2012098237-A1 | COMPOUNDS WITH SUPER-ASPIRIN EFFECTS | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2012-07-26 | — | — | WO | disclosed |
| US-20110046182-A1 | EFFICIENT ASPIRIN PRODRUGS | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABE (IE) | 2011-02-24 | — | — | US | disclosed |
| EP-2222681-A1 | EFFICIENT ASPIRIN PRODRUGS | The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth (IE) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009080795-A1 | EFFICIENT ASPIRIN PRODRUGS | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291615-A1 | COMPOUNDS WITH SUPER-ASPIRIN EFFECTS | HAO2, SCO2, AOC2 | PTPN1 1057/4885BCHE 2206/4885CES2 532/4885 |
| US-20140024681-A1 | COMPOUNDS WITH SUPER-ASPIRIN EFFECTS | HAO2, SCO2, NOS2 | PTPN1 421/4885BCHE 2475/4885CES2 457/4885 |
| US-20110046182-A1 | EFFICIENT ASPIRIN PRODRUGS | COX15, PTGS1, CYP3A43 | PTPN1 1214/4885BCHE 1941/4885CES2 1385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.