SCHEMBL4955426

SCHEMBL4955426

CCCCSCCC(N)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
BHMT Q93088 11/20 0.66
BHMT2 Q9H2M3 1/20 0.62
NOS2 P35228 2/20 0.57
NOS1 P29475 2/20 0.57
NOS3 P29474 1/20 0.57
SLC1A2 P43004 2/20 0.50
SLC1A1 P43005 2/20 0.50
SLC1A3 P43003 1/20 0.50
GRIK1 P39086 2/20 0.49
GRIK2 Q13002 2/20 0.49
DDAH1 O94760 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1285565 1.00 BHMT (0.66) BHMTBHMT2NOS2NOS1NOS3
SCHEMBL60520 1.00 BHMT (0.66) BHMTBHMT2NOS2NOS1NOS3
SCHEMBL18832133 0.94 BHMT (0.69) BHMTBHMT2NOS2NOS1NOS3
SCHEMBL17956289 0.93 BHMT (0.58) BHMTBHMT2NOS2NOS1NOS3
SCHEMBL11575012 0.93 BHMT (0.70) BHMTBHMT2NOS2NOS1NOS3
SCHEMBL18832139 0.93 BHMT (0.70) BHMTBHMT2NOS2NOS1NOS3
SCHEMBL18832141 0.93 BHMT (0.70) BHMTBHMT2NOS2NOS1NOS3
SCHEMBL2367840 0.93 BHMT (0.70) BHMTBHMT2NOS2NOS1NOS3
SCHEMBL18832137 0.93 BHMT (0.70) BHMTBHMT2NOS2NOS1NOS3
SCHEMBL2367837 0.93 BHMT (0.70) BHMTBHMT2NOS2NOS1NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US claimed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 US claimed
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2023-04-13 US claimed
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-11-24 US claimed
US-20190119322-A1 PREPARATION OF FUNCTIONAL HOMOCYSTEINE RESIDUES IN POLYPEPTIDES AND PEPTIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-04-25 US claimed
WO-2017189860-A1 PREPARATION OF FUNCTIONAL HOMOCYSTEINE RESIDUES IN POLYPEPTIDES AND PEPTIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-11-02 WO claimed
EP-4103144-B1 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2026-05-27 EP disclosed
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 US disclosed
WO-2026087745-A1 AN ANTIOXIDANT COMPOSITION COMPRISING A CINNAMIC ACID DERIVATIVE BRAIN Biotech AG (DE) 2026-04-30 WO disclosed
EP-4732825-A1 AN ANTIOXIDANT COMPOSITION COMPRISING A CINNAMIC ACID DERIVATIVE BRAIN Biotech AG (DE) 2026-04-29 EP disclosed
EP-4110277-B1 COMPOSITIONS COMPRISING (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2026-04-22 EP disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US disclosed
US-20260096978-A1 A METHOD FOR PREVENTING, MITIGATING AND/OR TREATING PTGS2-INDUCED SKIN DISORDERS AND RELATED DYSFUNCTIONS SYMRISE AG (DE) 2026-04-09 US disclosed
US-20050215623-A1 Palatability of aquaculture feed NOVUS INTERNATIONAL, INC. (US) 2005-09-29 US disclosed
EP-1531672-A2 ANTIMICROBIAL COMPOSITIONS Novus International, Inc. (US) 2005-05-25 EP disclosed
US-20040175434-A1 Antimicrobial compositions NOVUS INTERNATIONAL, INC. 2004-09-09 US disclosed
WO-2004019683-A2 ANTIMICROBIAL COMPOSITIONS NOVUS INTERNATIONAL, INC. (US) 2004-03-11 WO disclosed
US-5439803-A Using label derived from isotopically substituted glucose to measure relative activities of glycolysis and the pentose phosphate pathway THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1995-08-08 US disclosed
US-4055653-A Sulfur containing trialkoxybenzoylamino carboxylic acids DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1977-10-25 US disclosed
US-3981910-A Sulfur containing trialkoxybenzoylamino carboxylic acids DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1976-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351573-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM BHMT 282/4885BHMT2 150/4885NOS2 252/4885
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS BHMT 96/4885BHMT2 68/4885NOS2 864/4885
US-20190119322-A1 PREPARATION OF FUNCTIONAL HOMOCYSTEINE RESIDUES IN POLYPEPTIDES AND PEPTIDES BHMT2, BHMT, PTMS BHMT 2/4885BHMT2 1/4885NOS2 477/4885
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC BHMT 154/4885BHMT2 47/4885NOS2 2092/4885
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS DNPEP, NPEPPS, PAM BHMT 282/4885BHMT2 150/4885NOS2 252/4885
US-20050215623-A1 Palatability of aquaculture feed TAS2R3, TAS2R1, TAS2R20 BHMT 4314/4885BHMT2 3866/4885NOS2 1172/4885
US-20040175434-A1 Antimicrobial compositions MRPL21, FPR1, ARG1 BHMT 4126/4885BHMT2 4229/4885NOS2 438/4885
US-20260096978-A1 A METHOD FOR PREVENTING, MITIGATING AND/OR TREATING PTGS2-INDUCED SKIN DISORDERS AND RELATED DYSFUNCTIONS PTGS2, PTGES2, PTGS1 BHMT 1288/4885BHMT2 880/4885NOS2 26/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT BHMT 85/4885BHMT2 45/4885NOS2 1000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.