Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 5/20 | 0.39 |
| ▸ | CTSL | P07711 | 5/20 | 0.39 |
| ▸ | CTSS | P25774 | 4/20 | 0.39 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28547713 | 0.78 | ACE (0.49) | ACELTA4H | |
| SCHEMBL5915244 | 0.76 | PSMB5 (0.45) | ACE | |
| SCHEMBL1623850 | 0.75 | PLAU (0.41) | F2F3 | |
| SCHEMBL3880587 | 0.74 | REN (0.39) | ACE | |
| SCHEMBL28787568 | 0.73 | KDM4E (0.42) | CTSBCTSLCTSSCTSK | |
| SCHEMBL11026921 | 0.73 | ALDH1A1 (0.40) | — | |
| SCHEMBL10505327 | 0.73 | ALDH1A1 (0.40) | — | |
| SCHEMBL16198357 | 0.71 | LARS1 (0.42) | CTSBCTSLCTSSCTSKACE | |
| SCHEMBL16501164 | 0.69 | LTA4H (0.55) | ACELTA4H | |
| SCHEMBL10594093 | 0.69 | TAS1R3 (0.45) | CTSBCTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086136-A | Process for producing a peptide using a serine or thiol proteinase | (ZAIDANHOJIN) SAGAMI CHEMICAL RESEARCH CENTER (JA) | 1978-04-25 | — | — | US | disclosed |