Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20930584 | 0.82 | CYP2D6 (0.50) | HTTIDO1TDO2CYP2D6SRC | |
| SCHEMBL196782 | 0.80 | LMNA (0.52) | HTTIDO1TDO2CYP2D6SRC | |
| SCHEMBL8127769 | 0.80 | LMNA (0.52) | HTTIDO1TDO2CYP2D6SRC | |
| SCHEMBL8133019 | 0.80 | CES2 (0.45) | HTTIDO1TDO2CYP2D6SRC | |
| SCHEMBL196781 | 0.80 | LMNA (0.52) | HTTIDO1TDO2CYP2D6SRC | |
| SCHEMBL8133022 | 0.80 | CES2 (0.45) | HTTIDO1TDO2CYP2D6SRC | |
| SCHEMBL30670484 | 0.80 | LMNA (0.52) | HTTIDO1TDO2CYP2D6SRC | |
| SCHEMBL25240807 | 0.78 | IDO1 (0.43) | HTTIDO1TDO2CYP2D6SRC | |
| SCHEMBL4824347 | 0.78 | HTT (0.49) | HTTIDO1TDO2LMNAMAPK1 | |
| SCHEMBL1439143 | 0.78 | IDO1 (0.43) | HTTIDO1TDO2CYP2D6SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130514-A | RESIN, ADRENOCORTICOTROPIC ACTIVITY | ARMOUR PHARMACEUTICAL COMPANY (US) | 1978-12-19 | — | — | US | claimed |