Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | MMP12 | P39900 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
| ▸ | MMP16 | P51512 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214223 | 1.00 | HTT (0.49) | HTTPTGS2CXCL8MMP2MMP9 | |
| SCHEMBL4825414 | 1.00 | HTT (0.49) | HTTPTGS2CXCL8MMP2MMP9 | |
| SCHEMBL15695565 | 0.88 | HTT (0.49) | HTTPTGS2CXCL8MMP2MMP9 | |
| SCHEMBL29144510 | 0.88 | HTT (0.49) | HTTPTGS2CXCL8MMP2MMP9 | |
| SCHEMBL27600698 | 0.85 | HTT (0.50) | HTTPTGS2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL2204495 | 0.84 | PTGS2 (0.56) | PTGS2CXCL8MMP2MMP9MMP8 | |
| SCHEMBL8945731 | 0.84 | CXCL8 (0.44) | HTTPTGS2CXCL8MMP2MMP9 | |
| SCHEMBL286787 | 0.82 | CXCL8 (0.43) | HTTPTGS2CXCL8MMP2MMP9 | |
| SCHEMBL7595932 | 0.82 | PGR (0.47) | HTTPTGS2PTGS1CYP2C9CYP2C19 | |
| SCHEMBL9780871 | 0.82 | HTT (0.51) | HTTPTGS2CXCL8CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030120102-A1 | Method for the preparation of (s) -2-acetylthio-3-phenylpropionic acid | DSM IP ASSETS B.V. (NL) | 2003-06-26 | — | — | US | claimed |
| EP-1272466-A1 | METHOD FOR THE PREPARATION OF (S)-2-ACETYLTHIO-3-PHENYLPROPIONIC ACID | DSM N.V. (NL) | 2003-01-08 | — | — | EP | claimed |
| WO-2001058865-A1 | METHOD FOR THE PREPARATION OF (S)-2-ACETYLTHIO-3-PHENYLPROPIONIC ACID | DSM N.V. (NL) | 2001-08-16 | — | — | WO | claimed |
| US-20140135520-A1 | METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBOXYLIC ACID ESTER | Tokyo University of Science Educational Foundation Administration Organization (JP) | 2014-05-15 | — | — | US | disclosed |
| EP-2719679-A1 | METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBOXYLIC ACID ESTER | Tokyo University Of Science Educational Foundation Administrative Organization (JP) | 2014-04-16 | — | — | EP | disclosed |
| US-7388098-B2 | Dynamic resolution of isomers and resolved isomers | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-06-17 | — | — | US | disclosed |
| EP-1324975-B1 | DYNAMIC RESOLUTION OF ISOMERS AND RESOLVED ISOMERS | BRISTOL MYERS SQUIBB CO (US) | 2005-11-16 | — | — | EP | disclosed |
| EP-1324975-A2 | DYNAMIC RESOLUTION OF ISOMERS AND RESOLVED ISOMERS | Bristol-Myers Squibb Company (US) | 2003-07-09 | — | — | EP | disclosed |
| US-20020111512-A1 | Dynamic resolution of isomers and resolved isomers | BRISTOL-MYERS SQUIBB COMPANY | 2002-08-15 | — | — | US | disclosed |
| WO-2002028809-A2 | DYNAMIC RESOLUTION OF ISOMERS AND RESOLVED ISOMERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111512-A1 | Dynamic resolution of isomers and resolved isomers | DHCR24, LPAR1, SLC7A1 | HTT 1433/4885PTGS2 4335/4885CXCL8 1661/4885 |
| US-20140135520-A1 | METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBOXYLIC ACID ESTER | ALDH1A2, ADH1C, ADH1A | HTT 4247/4885PTGS2 2021/4885CXCL8 4618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.