Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30670484 | 1.00 | LMNA (0.52) | LMNAMAPK1GLSHTTKMT2A | |
| SCHEMBL196781 | 1.00 | LMNA (0.52) | LMNAMAPK1GLSHTTKMT2A | |
| SCHEMBL8127769 | 1.00 | LMNA (0.52) | LMNAMAPK1GLSHTTKMT2A | |
| SCHEMBL275598 | 0.84 | LMNA (0.64) | LMNAMAPK1KMT2APOLBPKM | |
| SCHEMBL9744991 | 0.82 | CES2 (0.57) | LMNAMAPK1GLSHTTKMT2A | |
| SCHEMBL29172241 | 0.81 | HTT (0.45) | LMNAMAPK1GLSHTTIDO1 | |
| SCHEMBL18512243 | 0.80 | CES2 (0.45) | LMNAMAPK1GLSHTTKMT2A | |
| SCHEMBL26669676 | 0.80 | CES2 (0.45) | LMNAMAPK1GLSHTTKMT2A | |
| SCHEMBL28553187 | 0.80 | HPGD (0.42) | LMNAMAPK1GLSHTTKMT2A | |
| SCHEMBL20930584 | 0.80 | CYP2D6 (0.50) | LMNAMAPK1HTTKMT2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113355367-B | Application of ketoacid reductase in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2024-03-26 | — | — | CN | claimed |
| US-20220325035-A1 | POLYESTER, POLYESTERAMIDE, AND POLYAMIDE COMPOSITIONS | IYER ANANTH V (US) | 2022-10-13 | — | — | US | claimed |
| CN-113355299-B | Ketoacid reductase, gene, engineering bacterium and application in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2022-05-24 | — | — | CN | claimed |
| CN-113355367-A | Application of ketoacid reductase in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2021-09-07 | — | — | CN | claimed |
| CN-113355299-A | Ketoacid reductase, gene, engineering bacterium and application in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2021-09-07 | — | — | CN | claimed |
| CN-108410831-B | Ketoacid reductase, gene, engineering bacterium and application in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2021-07-27 | — | — | CN | claimed |
| CN-113355367-B | Application of ketoacid reductase in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2024-03-26 | — | — | CN | disclosed |
| US-20220325035-A1 | POLYESTER, POLYESTERAMIDE, AND POLYAMIDE COMPOSITIONS | IYER ANANTH V (US) | 2022-10-13 | — | — | US | disclosed |
| CN-109689667-B | Porous chiral material and use thereof | 南开大学 | 2022-07-12 | — | — | CN | disclosed |
| CN-113355299-B | Ketoacid reductase, gene, engineering bacterium and application in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-113355367-A | Application of ketoacid reductase in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2021-09-07 | — | — | CN | disclosed |
| CN-113355299-A | Ketoacid reductase, gene, engineering bacterium and application in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2021-09-07 | — | — | CN | disclosed |
| CN-108410831-B | Ketoacid reductase, gene, engineering bacterium and application in synthesis of chiral aromatic 2-hydroxy acid | 浙江工业大学 | 2021-07-27 | — | — | CN | disclosed |
| WO-2003097810-A2 | NITRILASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | DIVERSA CORPORATION (US) | 2003-11-27 | — | — | WO | disclosed |
| US-6653498-B2 | Reacting an aldehyde with hydrogen cyanide in a water immiscible organic solvent and water, using the enzyme (R)-hydroxynitrile lyase | CLARIANT GMBH (DE) | 2003-11-25 | — | — | US | disclosed |
| US-20030124698-A1 | Which stereoselectively hydrolyze nitrites or cyanohydrins into acids and ammonia | DIVERSA CORPORATION | 2003-07-03 | — | — | US | disclosed |
| EP-1302458-A1 | ESTER DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-04-16 | — | — | EP | disclosed |
| WO-2003000840-A2 | NITRILASES | DIVERSA CORPORATION (US) | 2003-01-03 | — | — | WO | disclosed |
| EP-1219593-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINOALCOHOL | Mitsubishi Rayon Co., Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-20020052523-A1 | Process for preparing optically active cyanohydrins and secondary products | CLARIANT GMBH | 2002-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052523-A1 | Process for preparing optically active cyanohydrins and secondary products | DOHH, OGDH, AOX1 | LMNA 542/4885MAPK1 2827/4885GLS 894/4885 |
| US-20030124698-A1 | Which stereoselectively hydrolyze nitrites or cyanohydrins into acids and ammonia | NIT2, DNPH1, ASNS | LMNA 1094/4885MAPK1 4224/4885GLS 476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.