Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA4 | P22748 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24418066 | 0.97 | CA2 (0.40) | CA2CA4CA1CA6MAOA | |
| SCHEMBL9813429 | 0.77 | IGF1R (0.44) | CA2CA4CA1CA6MAOA | |
| SCHEMBL4799665 | 0.69 | IDO1 (0.37) | KDM4EHPGDALDH1A1 | |
| SCHEMBL9685153 | 0.69 | IGF1R (0.41) | KDM4EHPGDALDH1A1HSD17B10IGF1R | |
| SCHEMBL23638591 | 0.68 | HPGD (0.42) | KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL31128348 | 0.67 | ALDH1A1 (0.35) | KDM4EHPGDALDH1A1HSD17B10IGF1R | |
| SCHEMBL16153724 | 0.67 | MAOA (0.48) | CA2CA4CA1CA6MAOA | |
| SCHEMBL19254180 | 0.67 | IGF1R (0.40) | KDM4EHPGDALDH1A1HSD17B10IGF1R | |
| SCHEMBL14031539 | 0.67 | IGF1R (0.40) | KDM4EHPGDALDH1A1HSD17B10IGF1R | |
| SCHEMBL16850514 | 0.67 | IGF1R (0.45) | MAOADRD4DRD3HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4107104-A | TETRABROMOXYLENEDIOL - FLAME-RETARDANT FOR POLYURETHANES | ETHYL CORPORATION (US) | 1978-08-15 | — | — | US | disclosed |