Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8373097 | 0.84 | DRD4 (0.60) | DRD4MAOADRD3HPGDHSD17B10 | |
| SCHEMBL11577916 | 0.77 | CA2 (0.42) | IGF1RSRCAXLPTK2AURKB | |
| SCHEMBL9813428 | 0.76 | ALDH1A1 (0.37) | DRD4MAOADRD3HPGDHSD17B10 | |
| SCHEMBL9503945 | 0.75 | CA1 (0.55) | DRD4MAOADRD3HPGDHSD17B10 | |
| SCHEMBL9503900 | 0.75 | ALDH1A1 (0.39) | DRD4MAOADRD3HPGDHSD17B10 | |
| SCHEMBL24418066 | 0.75 | CA2 (0.40) | IGF1RSRCAXLPTK2AURKB | |
| SCHEMBL14031843 | 0.74 | IGF1R (0.50) | IGF1RSRCAXLPTK2AURKB | |
| SCHEMBL6825519 | 0.73 | ALDH1A1 (0.38) | DRD4MAOADRD3HPGDHSD17B10 | |
| SCHEMBL16854080 | 0.73 | IGF1R (0.48) | IGF1RSRCAXLPTK2AURKB | |
| SCHEMBL6825433 | 0.73 | DRD4 (0.56) | DRD4MAOADRD3HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260434-B1 | META-HALO-PHENOLIC ALKYLATION PRODUCTS AND EPOXY SYSTEMS | THE DOW CHEMICAL COMPANY (US) | 1991-08-07 | — | — | EP | disclosed |
| WO-1989001466-A1 | META-HALO-PHENOLIC ALKYLATION PRODUCTS AND EPOXY SYSTEMS | THE DOW CHEMICAL COMPANY (US) | 1989-02-23 | — | — | WO | disclosed |
| EP-0260434-A1 | Meta-halo-phenolic alkylation products and epoxy systems | THE DOW CHEMICAL COMPANY (US) | 1988-03-23 | — | — | EP | disclosed |
| US-4731423-A | Meta-halo-phenolic alkylation products and epoxy systems | THE DOW CHEMICAL COMPANY (US) | 1988-03-15 | — | — | US | disclosed |