SCHEMBL1158162

SCHEMBL1158162

CCCCCCSCC(NC(=O)CCC(N)C(=O)O)C(=O)NCC(=O)O

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.59
GSTK1 Q9Y2Q3 1/20 0.59
NOD1 Q9Y239 14/20 0.56
GLO1 Q04760 1/20 0.55
BHMT Q93088 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11870407 1.00 PTGS1 (0.59) PTGS1GSTK1NOD1GLO1BHMT
SCHEMBL6926435 1.00 PTGS1 (0.59) PTGS1GSTK1NOD1GLO1BHMT
SCHEMBL6927655 1.00 PTGS1 (0.59) PTGS1GSTK1NOD1GLO1BHMT
SCHEMBL11870393 1.00 PTGS1 (0.59) PTGS1GSTK1NOD1GLO1BHMT
SCHEMBL11866992 1.00 PTGS1 (0.59) PTGS1GSTK1NOD1GLO1BHMT
SCHEMBL17075565 1.00 PTGS1 (0.59) PTGS1GSTK1NOD1GLO1BHMT
SCHEMBL17075566 1.00 PTGS1 (0.59) PTGS1GSTK1NOD1GLO1BHMT
SCHEMBL2091563 1.00 PTGS1 (0.59) PTGS1GSTK1NOD1GLO1BHMT
SCHEMBL2091575 1.00 PTGS1 (0.59) PTGS1GSTK1NOD1GLO1BHMT
SCHEMBL11872484 1.00 PTGS1 (0.59) PTGS1GSTK1NOD1GLO1BHMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3270889-B1 TARGETED LIPOSOMAL DELIVERY OF CGMP ANALOGUES MIRECA MEDICINES GMBH (DE) 2024-02-07 EP claimed
WO-2022074181-A1 NANOCARRIER FORMULATIONS FOR INHALATION EnhanX Biopharm Inc. (TW) 2022-04-14 WO claimed
EP-3395372-B1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM ENHANX BIOPHARM INC (TW) 2022-04-06 EP claimed
EP-2459220-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2020-09-09 EP claimed
US-10322087-B2 Targeted liposomal delivery of cGMP analogues MIRECA MEDICINES GMBH (DE) 2019-06-18 US claimed
EP-2398500-B1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM 2 BBB MEDICINES B V (NL) 2019-03-13 EP claimed
EP-3395372-A1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM 2-BBB Medicines B.V. (NL) 2018-10-31 EP claimed
US-20180085311-A1 TARGETED LIPOSOMAL DELIVERY OF CGMP ANALOGUES MIRECA MEDICINES GMBH (DE) 2018-03-29 US claimed
EP-3270889-A1 TARGETED LIPOSOMAL DELIVERY OF CGMP ANALOGUES Mireca Medicines GmbH (DE) 2018-01-24 EP claimed
WO-2016146669-A1 TARGETED LIPOSOMAL DELIVERY OF CGMP ANALOGUES EBERHARD KARLS UNIVERSITÄT TÜBINGEN (DE) 2016-09-22 WO claimed
US-20140227185-A1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM TO-BBB HOLDING B.V. (NL) 2014-08-14 US claimed
US-20110305751-A1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM TO-BBB HOLDING B.V. (NL) 2011-12-15 US claimed
US-20060148020-A1 Inhibitors of gst a3-3 and gst a1-1 for the treatment of cancer MANNERVIK, BENGT (SE) 2006-07-06 US claimed
EP-1567645-A1 INHIBITORS OF GST A3-3 AND GST A1-1 FOR THE TREATMENT OF CANCER BIOVITRUM AB (SE) 2005-08-31 EP claimed
WO-2004048577-A1 INHIBITORS OF GST A3-3 AND GST A1-1 FOR THE TREATMENT OF CANCER BIOVITRUM AB (SE) 2004-06-10 WO claimed
EP-0645397-B1 Glutathione analogs and paralog panels comprising glutathione mimics TERRAPIN TECH INC (US) 1998-09-09 EP claimed
US-12617771-B2 Diphenylpyrazole compound, and preparation method therefor and application thereof NORTHWEST A&F UNIVERSITY (CN) 2026-05-05 US disclosed
US-12503636-B2 Corrosion inhibitor composition for wet sour crude KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2025-12-23 US disclosed
EP-0356838-A2 Chromatographic stationary supports AT BIOCHEM (US) 1990-03-07 EP disclosed
EP-0256223-A1 Herbicide tolerant plants containing a glutathione-S-transferase gene CIBA-GEIGY AG (CH) 1988-02-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10322087-B2 Targeted liposomal delivery of cGMP analogues PDE6C, PDE2A, GMPS PTGS1 131/4885GSTK1 64/4885NOD1 3854/4885
US-20110305751-A1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM GSS, GSTO1, SLC7A11 PTGS1 292/4885GSTK1 13/4885NOD1 3457/4885
US-20060148020-A1 Inhibitors of gst a3-3 and gst a1-1 for the treatment of cancer GSTA1, GSTK1, GSTM1 PTGS1 35/4885GSTK1 2/4885NOD1 3238/4885
US-12617771-B2 Diphenylpyrazole compound, and preparation method therefor and application thereof GSTP1, GSTO1, GSTA1 PTGS1 310/4885GSTK1 15/4885NOD1 986/4885
US-20180085311-A1 TARGETED LIPOSOMAL DELIVERY OF CGMP ANALOGUES PDE6C, PDE2A, GMPS PTGS1 131/4885GSTK1 71/4885NOD1 3852/4885
US-20140227185-A1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM GSS, GSTO1, SLC7A11 PTGS1 292/4885GSTK1 13/4885NOD1 3457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.