Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20382745 | 0.91 | LMNA (0.64) | KMT2ALMNASRD5A2PLA2G10PLA2G2A | |
| SCHEMBL20041199 | 0.89 | KMT2A (0.48) | KMT2ALMNAESR1ESR2SRD5A2 | |
| SCHEMBL18644564 | 0.83 | NOS3 (0.39) | KMT2ALMNAESR1ESR2PRSS1 | |
| SCHEMBL10308978 | 0.82 | ALDH1A1 (0.54) | KMT2APRSS1ALDH1A1TDP1CA2 | |
| SCHEMBL24620530 | 0.80 | LOXL2 (0.64) | PRSS1PRSS2PRSS3F10LOXL2 | |
| SCHEMBL11946753 | 0.80 | IDO1 (0.48) | KMT2ALMNAPRSS1PRSS2PRSS3 | |
| SCHEMBL23047513 | 0.78 | PLK1 (0.52) | KMT2ALMNAESR1ESR2ALDH1A1 | |
| SCHEMBL21324612 | 0.77 | LMNA (0.47) | KMT2ALMNAESR1ALDH1A1TSHR | |
| SCHEMBL19917504 | 0.77 | ALDH1A1 (0.50) | KMT2ALMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL9889057 | 0.77 | ESR1 (0.56) | KMT2ALMNAESR1ESR2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4066609-A | GLASS FABRIC OR FIBER | CIBA-GEIGY CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |
| US-3944525-A | Crosslinked resins prepared from an N,N'-bis-imide and a schiff base | CIBA-GEIGY CORPORATION (US) | 1976-03-16 | — | — | US | disclosed |