Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10599649 | 0.89 | KMT2A (0.58) | KMT2ALMNASRD5A2ESR1ESR2 | |
| SCHEMBL11583858 | 0.89 | KMT2A (0.58) | KMT2ALMNASRD5A2ESR1ESR2 | |
| SCHEMBL23950579 | 0.87 | GRIK2 (0.33) | LMNAPRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL10492823 | 0.81 | LMNA (0.64) | KMT2ALMNASRD5A2PLA2G10PLA2G2A | |
| SCHEMBL20382745 | 0.81 | LMNA (0.64) | KMT2ALMNASRD5A2PLA2G10PLA2G2A | |
| SCHEMBL23268269 | 0.80 | HSD17B1 (0.37) | ALDH1A1TDP1GRIK2 | |
| SCHEMBL18856115 | 0.79 | KMT2A (0.48) | KMT2ALMNASRD5A2ALDH1A1 | |
| SCHEMBL19072622 | 0.76 | KMT2A (0.45) | KMT2ALMNASRD5A2ESR1ESR2 | |
| SCHEMBL6704209 | 0.75 | THRB (0.44) | KMT2AESR1ESR2HDAC1THRA | |
| SCHEMBL18644564 | 0.74 | NOS3 (0.39) | KMT2ALMNAESR1ESR2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2714716-B1 | MATRIPTASE INHIBITORS AND USES THEREOF AGAINST ORTHOMYXOVIRIDAE INFECTIONS | SOCPRA SCIENCES SANTE ET HUMAINES S E C (CA) | 2018-04-11 | — | — | EP | disclosed |