Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 12/20 | 0.36 |
| ▸ | HTR2A | P28223 | 8/20 | 0.36 |
| ▸ | HTR1A | P08908 | 6/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.36 |
| ▸ | HTR1D | P28221 | 6/20 | 0.36 |
| ▸ | HTR2C | P28335 | 6/20 | 0.36 |
| ▸ | HTR1E | P28566 | 6/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.36 |
| ▸ | HRH1 | P35367 | 6/20 | 0.36 |
| ▸ | DRD3 | P35462 | 6/20 | 0.36 |
| ▸ | HTR2B | P41595 | 6/20 | 0.36 |
| ▸ | HTR6 | P50406 | 6/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.36 |
| ▸ | HTR1B | P28222 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11586280 | 0.75 | KDM4E (0.40) | OPRK1OPRM1OPRD1KDM4EALDH1A1 | |
| SCHEMBL11587798 | 0.74 | MTNR1A (0.35) | HTR2ASLC6A4SLC6A3SIGMAR1SLC6A2 | |
| SCHEMBL18320650 | 0.71 | OPRK1 (0.57) | OPRK1HTR2AHTR1AADRA2AADRA2B | |
| SCHEMBL6536337 | 0.68 | ALDH1A1 (0.47) | OPRK1HTR2AHTR1AADRA2AADRA2B | |
| SCHEMBL11587389 | 0.66 | MTNR1A (0.40) | HTR2AHTR2CSLC6A4HTR2BSLC6A3 | |
| SCHEMBL6661250 | 0.66 | AKR1B1 (0.34) | HTR2ASIGMAR1NQO2 | |
| SCHEMBL9621240 | 0.64 | NQO2 (0.40) | HTR2AKDM4EALDH1A1NQO2 | |
| SCHEMBL18589310 | 0.62 | CYP2D6 (0.56) | OPRK1HTR2AHTR1AADRA2AADRA2B | |
| SCHEMBL27628752 | 0.62 | HTR2A (0.50) | HTR2AHTR1AHTR1DHTR6KDM4E | |
| SCHEMBL24152350 | 0.62 | CYP2D6 (0.51) | OPRK1HTR2AHTR1AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108896-A | VIRICIDES | RICHARDSON-MERRELL INC. (US) | 1978-08-22 | — | — | US | disclosed |