Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.35 |
| ▸ | NQO2 | P16083 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11587389 | 0.78 | MTNR1A (0.40) | MTNR1ANQO2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6661250 | 0.74 | AKR1B1 (0.34) | MTNR1ANQO2HTR2AMTNR1BSIGMAR1 | |
| SCHEMBL11586285 | 0.74 | OPRK1 (0.36) | NQO2SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL11881368 | 0.73 | L3MBTL1 (0.45) | MTNR1ANQO2HTR2AMTNR1BL3MBTL1 | |
| SCHEMBL31274181 | 0.73 | L3MBTL1 (0.45) | MTNR1ANQO2HTR2AMTNR1BL3MBTL1 | |
| SCHEMBL11588676 | 0.72 | MTNR1A (0.39) | MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL11882341 | 0.70 | L3MBTL1 (0.42) | MTNR1ANQO2HTR2AMTNR1BL3MBTL1 | |
| SCHEMBL5252569 | 0.69 | TDP1 (0.46) | MTNR1ANQO2SIGMAR1SLC18A2 | |
| SCHEMBL11417146 | 0.69 | L3MBTL1 (0.41) | MTNR1AHTR2AMTNR1BSIGMAR1L3MBTL1 | |
| SCHEMBL11587793 | 0.69 | ALDH1A1 (0.41) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108896-A | VIRICIDES | RICHARDSON-MERRELL INC. (US) | 1978-08-22 | — | — | US | disclosed |