Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | CTSD | P07339 | 2/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | CTSE | P14091 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11569788 | 0.79 | OPRD1 (0.47) | SLC7A5 | |
| SCHEMBL11568492 | 0.75 | BACE1 (0.36) | BACE1 | |
| SCHEMBL11581066 | 0.74 | ANPEP (0.36) | BACE1CTSDCTSE | |
| SCHEMBL11568275 | 0.74 | SLC7A5 (0.40) | SLC7A5 | |
| SCHEMBL5551900 | 0.73 | SLC7A5 (0.52) | ALDH1A1SLC7A5LTA4H | |
| SCHEMBL11567184 | 0.73 | ALDH1A1 (0.47) | ALDH1A1BACE1CTSD | |
| SCHEMBL31039945 | 0.73 | CTSD (0.41) | ALDH1A1BACE1CTSDSLC7A5 | |
| SCHEMBL11566787 | 0.73 | ALDH1A1 (0.47) | ALDH1A1BACE1CTSD | |
| SCHEMBL11567194 | 0.73 | ALDH1A1 (0.47) | ALDH1A1BACE1CTSD | |
| SCHEMBL11566796 | 0.73 | ALDH1A1 (0.47) | ALDH1A1BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146614-A | TREATMENT OF SCHIZOPHRENIA | STATE OF MICHIGAN (US) | 1979-03-27 | — | — | US | disclosed |