Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.48 |
| ▸ | TOP1 | P11387 | 2/20 | 0.47 |
| ▸ | TOP2A | P11388 | 2/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.47 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SNCA | P37840 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11590152 | 0.84 | KCNMA1 (0.51) | HSD17B13TOP1TOP2ATOP2BSNCA | |
| SCHEMBL11589177 | 0.84 | RAB9A (0.57) | HSD17B13MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11588151 | 0.82 | NPC1 (0.66) | HSD17B13TOP1TOP2ATOP2BMEN1 | |
| SCHEMBL10011045 | 0.78 | KCNMA1 (0.57) | TOP1TOP2ATOP2BCXCR1MEN1 | |
| SCHEMBL12431978 | 0.78 | MEN1 (0.59) | TOP1CXCR1MEN1KMT2ANPC1 | |
| SCHEMBL21462534 | 0.76 | MDM4 (0.57) | MEN1KMT2ANPC1TP53RAB9A | |
| SCHEMBL27851528 | 0.75 | MAPT (0.51) | TOP1CXCR1MEN1KMT2ASNCA | |
| SCHEMBL11589160 | 0.75 | KCNMA1 (0.62) | HSD17B13TOP1TOP2ATOP2BSNCA | |
| SCHEMBL25349072 | 0.73 | RAB9A (0.64) | HSD17B13TOP1TOP2ATOP2BMEN1 | |
| SCHEMBL28463141 | 0.73 | TP53 (0.65) | HSD17B13TOP1TOP2ATOP2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4091097-A | A 2'-HYDROXY-3-CARBOXY-4,5-SUBSTITUTED-BENZANILIDE, ITS ESTERS AND SALTS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) | 1978-05-23 | — | — | US | disclosed |
| US-4024253-A | BENZANILIDE DERIVATIVES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) | 1977-05-17 | — | — | US | disclosed |