SCHEMBL12431978

SCHEMBL12431978

O=C(Nc1ccc(O)cc1O)c1cccc(C(=O)Nc2ccc(O)cc2O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.59
KMT2A Q03164 7/20 0.59
MAPT P10636 2/20 0.57
ALDH1A1 P00352 1/20 0.57
ABL1 P00519 1/20 0.57
TSHR P16473 1/20 0.57
RIN1 Q13671 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
PKM P14618 1/20 0.56
GFER P55789 1/20 0.54
AKR1C4 P17516 3/20 0.54
AKR1C3 P42330 3/20 0.54
AKR1C2 P52895 3/20 0.54
AKR1C1 Q04828 3/20 0.54
RAB9A P51151 2/20 0.53
KCNMA1 Q12791 1/20 0.51
CXCR1 P25024 1/20 0.51
PABPC1 P11940 1/20 0.51
DUSP3 P51452 1/20 0.51
PTPN5 P54829 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10011045 0.89 KCNMA1 (0.57) MEN1KMT2AMAPTALDH1A1ABL1
SCHEMBL462324 0.81 MEN1 (0.66) MEN1KMT2APKMRAB9AKCNMA1
SCHEMBL30403027 0.81 KCNMA1 (0.63) MAPTALDH1A1TSHRTDP1KCNMA1
SCHEMBL22083644 0.81 PARP1 (0.62) MEN1KMT2AMAPTALDH1A1ABL1
SCHEMBL17544193 0.81 KCNMA1 (0.63) MAPTALDH1A1TSHRTDP1KCNMA1
SCHEMBL6799613 0.81 MEN1 (0.58) MEN1KMT2AALDH1A1PKMAKR1C4
SCHEMBL12510860 0.80 HDAC1 (0.55) MEN1KMT2AMAPTALDH1A1ABL1
SCHEMBL27851528 0.79 MAPT (0.51) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL11590445 0.79 ALDH1A1 (0.61) MEN1KMT2AMAPTALDH1A1ABL1
SCHEMBL11588024 0.78 HSD17B13 (0.48) MEN1KMT2AMAPTALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1909142-B1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES (JP) 2015-06-24 EP disclosed
US-7977028-B2 Photosensitive resin composition and adhesion promoter TORAY INDUSTRIES, INC. (JP) 2011-07-12 US disclosed
US-7977028-B2 Photosensitive resin composition and adhesion promoter TORAY INDUSTRIES, INC. (JP) 2011-07-12 US disclosed
US-7615324-B2 Photosensitive composition, and cured relief pattern production method and semiconductor device using the same FUJIFILM CORPORATION (JP) 2009-11-10 US disclosed
US-7615324-B2 Photosensitive composition, and cured relief pattern production method and semiconductor device using the same FUJIFILM CORPORATION (JP) 2009-11-10 US disclosed
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER TORAY INDUSTRIES, INC. (JP) 2009-05-14 US disclosed
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER TORAY INDUSTRIES, INC. (JP) 2009-05-14 US disclosed
US-7455948-B2 Photosensitive resin composition TORAY INDUSTRIES, INC. (JP) 2008-11-25 US disclosed
US-7455948-B2 Photosensitive resin composition TORAY INDUSTRIES, INC. (JP) 2008-11-25 US disclosed
US-20080227024-A1 PHOTOSENSITIVE COMPOSITION, AND CURED RELIEF PATTERN PRODUCTION METHOD AND SEMICONDUCTOR DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2008-09-18 US disclosed
US-20080227024-A1 PHOTOSENSITIVE COMPOSITION, AND CURED RELIEF PATTERN PRODUCTION METHOD AND SEMICONDUCTOR DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2008-09-18 US disclosed
EP-1909142-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES, INC. (JP) 2008-04-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER PCNA, TERB1, SMC2 MEN1 4387/4885KMT2A 56/4885MAPT 1072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.