Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.66 |
| ▸ | TOP1 | P11387 | 2/20 | 0.62 |
| ▸ | TOP2A | P11388 | 1/20 | 0.62 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.62 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TERT | O14746 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11589239 | 0.90 | NPC1 (0.57) | NPC1MEN1KMT2ARAB9ATP53 | |
| SCHEMBL11589478 | 0.88 | MEN1 (0.56) | NPC1MEN1KMT2ARAB9ATP53 | |
| SCHEMBL11588066 | 0.87 | MEN1 (0.62) | NPC1MEN1KMT2ARAB9ATP53 | |
| SCHEMBL11590512 | 0.85 | NPC1 (0.69) | NPC1MEN1KMT2ARAB9ATP53 | |
| SCHEMBL25349072 | 0.84 | RAB9A (0.64) | NPC1MEN1KMT2ARAB9ATOP1 | |
| SCHEMBL28463141 | 0.84 | TP53 (0.65) | NPC1MEN1KMT2ARAB9ATP53 | |
| SCHEMBL11588005 | 0.83 | TAS1R3 (0.75) | NPC1MEN1KMT2ARAB9ATP53 | |
| SCHEMBL11588024 | 0.82 | HSD17B13 (0.48) | NPC1MEN1KMT2ARAB9ATP53 | |
| SCHEMBL3864321 | 0.81 | TOP1 (0.62) | NPC1MEN1KMT2ARAB9ATP53 | |
| SCHEMBL11587889 | 0.80 | TOP1 (0.62) | NPC1MEN1KMT2ARAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4091097-A | A 2'-HYDROXY-3-CARBOXY-4,5-SUBSTITUTED-BENZANILIDE, ITS ESTERS AND SALTS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) | 1978-05-23 | — | — | US | disclosed |
| US-4024253-A | BENZANILIDE DERIVATIVES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) | 1977-05-17 | — | — | US | disclosed |