Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 6/20 | 0.35 |
| ▸ | PPARD | Q03181 | 6/20 | 0.35 |
| ▸ | PPARA | Q07869 | 6/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5445954 | 0.94 | CA2 (0.33) | AKR1B1ACE2ARG1ARG2GPR84 | |
| SCHEMBL28374751 | 0.86 | CES2 (0.40) | CES2ACE2PPARGPPARDPPARA | |
| SCHEMBL6861100 | 0.86 | CES2 (0.42) | CES2 | |
| SCHEMBL29184106 | 0.85 | ALDH1A1 (0.33) | ARG1ARG2TSHRALDH1A1TDP1 | |
| SCHEMBL28416846 | 0.85 | CES2 (0.39) | CES2ACE2PPARGPPARDPPARA | |
| SCHEMBL27823774 | 0.85 | GPR84 (0.41) | CES2ACE2GPR84FFAR1FFAR4 | |
| SCHEMBL31175366 | 0.84 | ALDH1A1 (0.53) | PPARGPPARDPPARATSHRALDH1A1 | |
| SCHEMBL3554641 | 0.82 | SMPD1 (0.40) | CES2PPARGPPARDPPARAHDAC11 | |
| SCHEMBL8012921 | 0.82 | ACE2 (0.43) | ACE2PPARDGPR84FFAR1FFAR4 | |
| SCHEMBL8029009 | 0.82 | ACE2 (0.43) | ACE2PPARDGPR84FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086304-A | SALT OF A METAL OF GROUP I OR II AND AN ORGANIC ACID | AKZONA INCORPORATED (US) | 1978-04-25 | — | — | US | disclosed |