Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 5/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11589606 | 0.79 | ALDH1A1 (0.54) | KDM4EALDH1A1MAPTTHRBHPGD | |
| SCHEMBL5871967 | 0.75 | FEN1 (0.54) | KDM4EALDH1A1MAPTTHRBHPGD | |
| SCHEMBL9037765 | 0.71 | RXFP1 (0.50) | KDM4EALDH1A1MAPTLMNATSHR | |
| SCHEMBL24879507 | 0.68 | SCN5A (0.40) | ALDH1A1MAPTHSD17B10TSHRHTT | |
| SCHEMBL6403829 | 0.67 | BACE1 (0.49) | KDM4EBACE1BRPF1 | |
| SCHEMBL2439702 | 0.67 | HSD17B10 (0.38) | KDM4EALDH1A1MAPTTHRBHPGD | |
| SCHEMBL29205998 | 0.67 | FEN1 (0.41) | KDM4EALDH1A1MAPTTHRBHPGD | |
| SCHEMBL30846793 | 0.67 | FEN1 (0.41) | KDM4EALDH1A1MAPTTHRBHPGD | |
| SCHEMBL30060872 | 0.67 | KDM4E (0.42) | KDM4EALDH1A1HPGDLMNAGAA | |
| SCHEMBL2434550 | 0.66 | ADORA1 (0.45) | KDM4EALDH1A1MAPTTHRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4103257-A | BLUE TO NEAR ULTRAVIOLET | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1978-07-25 | — | — | US | disclosed |