Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.61 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.54 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6643666 | 0.90 | LMNA (0.67) | LMNAHIF1AROCK2ROCK1HDAC1 | |
| SCHEMBL11591966 | 0.84 | LMNA (0.69) | LMNAHIF1AROCK2ROCK1HDAC1 | |
| SCHEMBL10483317 | 0.83 | HDAC1 (0.56) | LMNAHIF1AROCK2ROCK1HDAC1 | |
| SCHEMBL4542768 | 0.82 | BCAT2 (0.58) | HTTL3MBTL1NAMPTNPC1RAB9A | |
| SCHEMBL23406076 | 0.79 | CYP2A6 (0.55) | LMNAHIF1AROCK2ROCK1HDAC1 | |
| SCHEMBL29743805 | 0.79 | CYP2A6 (0.55) | LMNAHIF1AROCK2ROCK1HDAC1 | |
| SCHEMBL29199014 | 0.78 | LMNA (0.56) | LMNAHIF1AROCK2ROCK1HDAC1 | |
| SCHEMBL19520187 | 0.78 | LMNA (0.81) | LMNAHIF1AROCK2ROCK1HDAC1 | |
| SCHEMBL11591085 | 0.78 | HDAC1 (0.60) | LMNAHIF1AROCK2ROCK1HDAC1 | |
| SCHEMBL11591466 | 0.78 | HDAC1 (0.60) | LMNAHIF1AROCK2ROCK1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4098892-A | ANTIULCER AGENTS AND DIURETICS | NIPPON SHINYAKU CO., LTD. (JP) | 1978-07-04 | — | — | US | claimed |
| US-4098892-A | ANTIULCER AGENTS AND DIURETICS | NIPPON SHINYAKU CO., LTD. (JP) | 1978-07-04 | — | — | US | disclosed |