Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211110 | 0.81 | HSD17B10 (0.45) | TSHRHTTALDH1A1LMNAKMT2A | |
| SCHEMBL11214201 | 0.75 | LMNA (0.47) | KDM4EHTTALDH1A1LMNAKMT2A | |
| SCHEMBL10998181 | 0.73 | NQO1 (0.46) | KDM4EEPHX1TSHRHTTLMNA | |
| SCHEMBL11393589 | 0.72 | KDM4E (0.55) | KDM4EEPHX1TSHRHTTALDH1A1 | |
| SCHEMBL11208904 | 0.72 | CYP2C9 (0.40) | KDM4ETSHRHTTALDH1A1LMNA | |
| SCHEMBL10497899 | 0.71 | CYP3A4 (0.68) | KDM4EEPHX1TSHRHTTLMNA | |
| SCHEMBL9182141 | 0.71 | EPHX1 (0.74) | KDM4EEPHX1TSHRHTTALDH1A1 | |
| SCHEMBL11434471 | 0.71 | TDP1 (0.45) | KDM4EALDH1A1LMNAKMT2ATDP1 | |
| SCHEMBL11705566 | 0.71 | ALDH1A1 (0.56) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11342978 | 0.70 | KDM4E (0.46) | KDM4EEPHX1TSHRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004611-A1 | Process for the preparation of acetoacetylaryl amides | CIBA-GEIGY AG (CH) | 1979-10-17 | — | — | EP | disclosed |