Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206968 | 0.86 | MTNR1B (0.56) | MTNR1AMTNR1B | |
| SCHEMBL11210194 | 0.78 | CRHBP (0.44) | MAPK1MAPTSMN1; SMN2KMT2AHPGD | |
| SCHEMBL9505366 | 0.78 | ALDH1A1 (0.46) | LMNAALDH1A1SMN1; SMN2KMT2AHTT | |
| SCHEMBL15266769 | 0.77 | ALDH1A1 (0.48) | LMNAMAPK1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL11429495 | 0.76 | MAPT (0.44) | LMNAALDH1A1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL11596353 | 0.75 | KDM4E (0.50) | LMNAALDH1A1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL11524158 | 0.75 | TP53 (0.57) | LMNAMAPK1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL9411919 | 0.75 | MTNR1A (0.46) | LMNAALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL59241 | 0.73 | APP (0.58) | LMNAMAPK1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL26624253 | 0.73 | MTNR1A (0.53) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025164-B1 | DISAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-04-13 | — | — | EP | disclosed |
| EP-0025164-A1 | Disazo compounds, process for their preparation and use | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-03-18 | — | — | EP | disclosed |