Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | JUN | P05412 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2975268 | 0.85 | PAX8 (0.44) | HSD17B10MTNR1AMTNR1BNPSR1KMT2A | |
| SCHEMBL11208904 | 0.85 | CYP2C9 (0.40) | HSD17B10MTNR1AMTNR1BKMT2AALDH1A1 | |
| SCHEMBL11434471 | 0.84 | TDP1 (0.45) | KMT2AALDH1A1MAPTMAPK1TP53 | |
| SCHEMBL11705566 | 0.84 | ALDH1A1 (0.56) | NPSR1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL11596353 | 0.81 | KDM4E (0.50) | MTNR1AMTNR1BKMT2AALDH1A1MAPT | |
| SCHEMBL11222060 | 0.77 | HSD17B1 (0.46) | MTNR1AMTNR1BALDH1A1MAPTCYP1A2 | |
| SCHEMBL11206968 | 0.74 | MTNR1B (0.56) | MTNR1AMTNR1B | |
| SCHEMBL27572161 | 0.73 | MAPT (0.46) | HSD17B10MTNR1AMTNR1BNPSR1KMT2A | |
| SCHEMBL5406017 | 0.71 | KMT2A (0.73) | NPSR1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL24325399 | 0.71 | HSD17B10 (0.43) | HSD17B10MTNR1AMTNR1BNPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025164-B1 | DISAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-04-13 | — | — | EP | disclosed |
| EP-0025164-A1 | Disazo compounds, process for their preparation and use | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-03-18 | — | — | EP | disclosed |
| US-4221709-A | Azo pigments | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 1980-09-09 | — | — | US | disclosed |