Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 2/20 | 0.42 |
| ▸ | ARG1 | P05089 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 4/20 | 0.37 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | PLAU | P00749 | 3/20 | 0.37 |
| ▸ | PLAT | P00750 | 3/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11594293 | 0.98 | SNCA (0.43) | SNCATOP1ARG1ERCC1ERCC4 | |
| SCHEMBL14868391 | 0.84 | SNCA (0.40) | SNCATOP1ARG1ERCC1ERCC4 | |
| SCHEMBL10310173 | 0.82 | ALDH1A1 (0.51) | ALOX15F2F10PLAUPLAT | |
| SCHEMBL11593474 | 0.82 | PDE10A (0.45) | ALOX15F2F10PLAUPLAT | |
| SCHEMBL11128532 | 0.82 | ALOX15 (0.43) | SNCAALOX15F2F10PLAU | |
| SCHEMBL11133331 | 0.81 | ALOX15 (0.47) | SNCATOP1ARG1ERCC1ERCC4 | |
| SCHEMBL11275768 | 0.81 | PYGL (0.49) | SNCATOP1ERCC1ERCC4ALOX15 | |
| Hydrochloric Acid SCHEMBL11511126 | 0.80 | ALDH1A1 (0.45) | MAOAMAOB | |
| SCHEMBL11595524 | 0.79 | XDH (0.46) | F2F10PLAUPLATPRSS1 | |
| SCHEMBL30506422 | 0.78 | KMT2A (0.57) | SNCATOP1ARG1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4014934-A | VASOCONSTRICTORS | ARMOUR PHARMACEUTICAL COMPANY (US) | 1977-03-29 | — | — | US | claimed |
| US-4109014-A | VASOCONSTRICTORS | ARMOUR PHARMACEUTICAL COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4060554-A | VASOCONSTRICTORS | ARMOUR PHARMACEUTICAL COMPANY (US) | 1977-11-29 | — | — | US | disclosed |
| US-4014934-A | VASOCONSTRICTORS | ARMOUR PHARMACEUTICAL COMPANY (US) | 1977-03-29 | — | — | US | disclosed |