Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.59 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 8/20 | 0.54 |
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | TYK2 | P29597 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7379264 | 0.86 | KCNK3 (0.71) | KCNK3KCNK9NPC1RAB9AMEN1 | |
| SCHEMBL363342 | 0.84 | PTPN1 (0.67) | KCNK3KCNK9PTPN1NPC1RAB9A | |
| SCHEMBL22305399 | 0.82 | KCNK3 (0.83) | KCNK3KCNK9PTPN1NPC1RAB9A | |
| SCHEMBL363881 | 0.80 | PTPN1 (0.67) | KCNK3KCNK9PTPN1NPC1RAB9A | |
| SCHEMBL24202631 | 0.76 | SIRT1 (0.83) | KCNK3KCNK9PTPN1NPC1RAB9A | |
| SCHEMBL126415 | 0.76 | PTPN1 (0.87) | KCNK3KCNK9PTPN1NPC1RAB9A | |
| N-Phenylbenzamide SCHEMBL5402750 | 0.76 | SIRT1 (0.83) | KCNK3KCNK9PTPN1NPC1RAB9A | |
| N-Phenylbenzamide SCHEMBL31966 | 0.76 | SIRT1 (0.83) | KCNK3KCNK9PTPN1NPC1RAB9A | |
| SCHEMBL1486873 | 0.76 | NQO2 (0.75) | KCNK3KCNK9PTPN1NPC1RAB9A | |
| SCHEMBL6866111 | 0.76 | L3MBTL1 (0.85) | KCNK3KCNK9PTPN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118232-A | Photographic material containing sulphonic acid group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1978-10-03 | — | — | US | claimed |
| US-4118232-A | Photographic material containing sulphonic acid group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1978-10-03 | — | — | US | disclosed |
| US-4051123-A | Sulfonic-acid-group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1977-09-27 | — | — | US | disclosed |