SCHEMBL11599090

SCHEMBL11599090

Cc1ccc(SCCOP(OCCSc2ccc(C)cc2Cl)OCCSc2ccc(C)cc2Cl)c(Cl)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.34
MAPT P10636 5/20 0.34
RAB9A P51151 5/20 0.34
ATM Q13315 1/20 0.34
HPGD P15428 5/20 0.33
NPC1 O15118 4/20 0.33
CYP2C9 P11712 3/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CYP2C19 P33261 2/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
ALOX12 P18054 1/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14733971 0.67 PKM (0.44) L3MBTL1MAPTRAB9AHPGDNPC1
SCHEMBL20056723 0.67 LMNA (0.40) L3MBTL1RAB9AHPGDSMN1; SMN2POLB
SCHEMBL23912809 0.67 CYP1A2 (0.40) L3MBTL1MAPTRAB9AATMHPGD
SCHEMBL13461858 0.67 LMNA (0.41) MAPTRAB9AHPGDNPC1CYP2C9
SCHEMBL25447136 0.65 CYP1A2 (0.39) L3MBTL1MAPTRAB9AATMHPGD
SCHEMBL6235213 0.63 NPC1 (0.44) MAPTRAB9AHPGDNPC1CYP2C9
SCHEMBL9515924 0.63 LMNA (0.45) L3MBTL1MAPTRAB9AHPGDNPC1
SCHEMBL11867054 0.62 GAA (0.51) L3MBTL1MAPTHPGDKMT2ASMN1; SMN2
SCHEMBL13678418 0.62 CYP1A2 (0.37) MAPTRAB9AHPGDNPC1CYP2C9
SCHEMBL24564675 0.61 CYP1A2 (0.41) L3MBTL1MAPTRAB9AATMHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE29523-E Olefinic polymers stabilized with thioacyl trivalent phosphorus compounds BORG-WARNER CORPORATION (US) 1978-01-24 US disclosed