Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11599734 | 0.96 | MEN1 (0.42) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL11599724 | 0.90 | MAPT (0.45) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL11600615 | 0.86 | MEN1 (0.41) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL11600447 | 0.82 | CA12 (0.41) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL11599360 | 0.78 | AKR1C3 (0.41) | MEN1KMT2ALMNAMAPTGAA | |
| SCHEMBL11599650 | 0.75 | ALDH1A1 (0.51) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL11600056 | 0.75 | LTA4H (0.56) | MEN1KMT2ALMNAMAPTESR1 | |
| SCHEMBL11598835 | 0.75 | MAPK1 (0.48) | RAB9ALMNAMAPTHPGD | |
| SCHEMBL11600851 | 0.74 | ALDH1A1 (0.46) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL11555138 | 0.73 | MEN1 (0.44) | MEN1KMT2ARAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4093570-A | CROSSLINKABLE, MIXED ORGANIC MEDIUM; | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) | 1978-06-06 | — | — | US | disclosed |
| US-4075227-A | NONSTEROIDAL | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |