Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11599564 | 0.96 | MEN1 (0.44) | MEN1KMT2AGAAUSP2KEAP1 | |
| SCHEMBL11600615 | 0.90 | MEN1 (0.41) | MEN1KMT2AGAAUSP2KEAP1 | |
| SCHEMBL11599724 | 0.86 | MAPT (0.45) | MEN1KMT2AGAARAB9AMAPT | |
| SCHEMBL11600447 | 0.85 | CA12 (0.41) | MEN1KMT2AGAARAB9AMAPT | |
| SCHEMBL11598835 | 0.79 | MAPK1 (0.48) | RAB9AMAPTLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL11600056 | 0.79 | LTA4H (0.56) | MEN1KMT2AUSP2MAPTLMNA | |
| SCHEMBL11599360 | 0.77 | AKR1C3 (0.41) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL11600694 | 0.76 | KAT6A (0.39) | KMT2APOLB | |
| SCHEMBL11600648 | 0.76 | ALDH1A1 (0.45) | MEN1KMT2AGAARAB9AMAPT | |
| SCHEMBL11599650 | 0.74 | ALDH1A1 (0.51) | MEN1KMT2ARAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075227-A | NONSTEROIDAL | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |