Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | LIG1 | P18858 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.37 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11599564 | 0.90 | MEN1 (0.44) | MAPTLMNAMEN1KMT2ARAB9A | |
| SCHEMBL11599360 | 0.88 | AKR1C3 (0.41) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL11599734 | 0.86 | MEN1 (0.42) | MAPTLMNAMEN1KMT2ARAB9A | |
| SCHEMBL11600447 | 0.85 | CA12 (0.41) | MAPTLMNAMEN1KMT2ARAB9A | |
| SCHEMBL11600615 | 0.85 | MEN1 (0.41) | MAPTLMNAMEN1KMT2ARAB9A | |
| SCHEMBL11599650 | 0.84 | ALDH1A1 (0.51) | MAPTMEN1KMT2ARAB9AHTT | |
| SCHEMBL11602662 | 0.81 | KMT2A (0.43) | MAPTLMNAMEN1KMT2ARAB9A | |
| SCHEMBL11548807 | 0.79 | LMNA (0.46) | MAPTLMNAMEN1KMT2ARAB9A | |
| SCHEMBL11598774 | 0.78 | EPHX2 (0.41) | LMNAMEN1KMT2ARAB9AHTT | |
| SCHEMBL11600143 | 0.78 | RARB (0.47) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075227-A | NONSTEROIDAL | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |