Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | CASP6 | P55212 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.63 |
| ▸ | PLAU | P00749 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30292799 | 1.00 | LMNA (1.00) | LMNAKDM4EPOLBCASP6CYP1A2 | |
| Hydrochloric Acid SCHEMBL2247003 | 0.98 | KDM4E (0.96) | LMNAKDM4EPOLBCASP6CYP1A2 | |
| SCHEMBL31538470 | 0.84 | LMNA (0.73) | LMNAKDM4EPOLBCASP6CYP1A2 | |
| SCHEMBL1348618 | 0.84 | LMNA (0.73) | LMNAKDM4EPOLBCASP6CYP1A2 | |
| SCHEMBL14925242 | 0.80 | LMNA (0.66) | LMNAKDM4EPOLBCASP6CYP1A2 | |
| SCHEMBL161703 | 0.77 | CYP1A2 (1.00) | LMNAKDM4EPOLBCASP6CYP1A2 | |
| SCHEMBL30503638 | 0.77 | PLAU (1.00) | LMNAKDM4EPOLBCASP6PLAU | |
| SCHEMBL3412309 | 0.77 | PLAU (1.00) | LMNAKDM4EPOLBCASP6PLAU | |
| SCHEMBL29444268 | 0.77 | CYP1A2 (1.00) | LMNAKDM4EPOLBCASP6CYP1A2 | |
| SCHEMBL10259445 | 0.76 | CYP1A2 (0.68) | LMNAKDM4EPOLBCASP6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 478 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118001879-A | Application of nano copper alloy in filtering harmful substances in cigarette smoke | 广东合一新材料研究院有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-111377860-A | Cyanide/hydrogen cyanide colorimetric-fluorescent probe and detection test paper and preparation method thereof | 中国科学技术大学 | 2020-07-07 | — | — | CN | claimed |
| CN-108358914-B | Nucleic acid fluorescent probe for cell nucleus staining and preparation method thereof | 中国科学技术大学 | 2020-03-31 | — | — | CN | claimed |
| US-10401747-B1 | Undercoat layer for imaging device | XEROX CORPORATION (US) | 2019-09-03 | — | — | US | claimed |
| EP-2935198-B1 | METHOD FOR STABILISING POLYMERISABLE COMPOUNDS | BASF SE (DE) | 2019-06-05 | — | — | EP | claimed |
| CN-109020886-A | Alkylaminoquinoline class compound and its preparation method and application | 中国人民解放军成都军区总医院 | 2018-12-18 | — | — | CN | claimed |
| CN-108358914-A | A kind of nucleic acid fluorescent probe and preparation method thereof for nuclear targeting | 中国科学技术大学 | 2018-08-03 | — | — | CN | claimed |
| EP-2119717-B1 | 8-[3-amino-piperidin-1-yl]-xanthins, their production and utilisation as DPP IV inhibitors | BOEHRINGER INGELHEIM INT (DE) | 2018-01-17 | — | — | EP | claimed |
| EP-2935198-A2 | METHOD FOR STABILISING POLYMERISABLE COMPOUNDS | BASF SE (DE) | 2015-10-28 | — | — | EP | claimed |
| WO-2014095437-A2 | METHOD FOR STABILISING POLYMERISABLE COMPOUNDS | BASF SE (DE) | 2014-06-26 | — | — | WO | claimed |
| US-20100166765-A1 | BENZOQUINAZOLINE DERIVATIVES | NOVARTIS AG (CH) | 2010-07-01 | — | — | US | claimed |
| EP-1917246-B1 | BENZOQUINAZOLINE DERIVATIVES AND THEIR USE IN TREATING BONE DISORDERS | NOVARTIS AG (CH) | 2009-11-11 | — | — | EP | claimed |
| US-20090246660-A1 | ADDITIVE CONTAINING PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-10-01 | — | — | US | claimed |
| US-20090137801-A1 | 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-28 | — | — | US | claimed |
| EP-1758905-B1 | 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINE, THE PRODUCTION THEREOF AND THE USE IN THE FORM OF A DDP-IV INHIBITOR | BOEHRINGER INGELHEIM INT (DE) | 2009-04-29 | — | — | EP | claimed |
| EP-1917246-A1 | BENZOQUINAZOLINE DERIVATIVES AND THEIR USE IN TREATING BONE DISORDERS | Novartis AG (CH) | 2008-05-07 | — | — | EP | claimed |
| WO-2007020046-A1 | BENZOQUINAZOLINE DERIVATIVES AND THEIR USE IN TREATING BONE DISORDERS | NOVARTIS AG (CH) | 2007-02-22 | — | — | WO | claimed |
| US-20050234108-A1 | 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-10-20 | — | — | US | claimed |
| US-20040110778-A1 | Heterocyclic compounds as ligands of the GABAA receptor | YOHANNES DANIEL (US) | 2004-06-10 | — | — | US | claimed |
| US-20030105081-A1 | Heterocyclic compounds as ligands of the GABAA receptor | PFIZER INC | 2003-06-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105081-A1 | Heterocyclic compounds as ligands of the GABAA receptor | GABRB1, GABRP, GABRA1 | LMNA 3137/4885KDM4E 2087/4885POLB 3619/4885 |
| US-20090137801-A1 | 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | DPP8, DPP4, DPP7 | LMNA 2911/4885KDM4E 1036/4885POLB 2194/4885 |
| US-20040110778-A1 | Heterocyclic compounds as ligands of the GABAA receptor | GABRB1, GABRP, GABRA1 | LMNA 3137/4885KDM4E 2087/4885POLB 3619/4885 |
| US-20100166765-A1 | BENZOQUINAZOLINE DERIVATIVES | CACNA1A, BMP4, TPX2 | LMNA 2088/4885KDM4E 274/4885POLB 4222/4885 |
| US-20050234108-A1 | 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions | DPP8, DPP4, DPP7 | LMNA 1878/4885KDM4E 1140/4885POLB 2648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.