Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17831338 | 0.98 | HTT (0.41) | CA12CA1CA2CA9HTT | |
| SCHEMBL258456 | 0.95 | CA12 (0.41) | CA12CA1CA2CA9HTT | |
| SCHEMBL258261 | 0.92 | THRB (0.44) | CA12CA1CA2CA9HTT | |
| SCHEMBL6267890 | 0.92 | THRB (0.44) | CA12CA1CA2CA9HTT | |
| SCHEMBL1260510 | 0.92 | THRB (0.44) | CA12CA1CA2CA9HTT | |
| SCHEMBL456550 | 0.92 | THRB (0.44) | CA12CA1CA2CA9HTT | |
| SCHEMBL8177542 | 0.92 | TSHR (0.39) | CA12CA1CA2CA9HTT | |
| SCHEMBL14351508 | 0.92 | THRB (0.44) | CA12CA1CA2CA9HTT | |
| SCHEMBL15722834 | 0.92 | THRB (0.44) | CA12CA1CA2CA9HTT | |
| SCHEMBL164198 | 0.92 | THRB (0.44) | CA12CA1CA2CA9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3553068-B1 | YDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM | ICL IP AMERICA INC (US) | 2021-04-28 | — | — | EP | disclosed |
| EP-3553068-A1 | HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM | ICL-IP America Inc. (US) | 2019-10-16 | — | — | EP | disclosed |
| EP-2909218-B1 | METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM | ICL IP AMERICA INC (US) | 2019-07-10 | — | — | EP | disclosed |
| CN-105503946-B | The manufacturing method of hydroxymethyl phosphonic acid ester, polyurethane foam formation composition, polyurethane foam and the product being made from it | ICL-IP美国公司 | 2018-10-12 | — | — | CN | disclosed |
| CN-107383093-A | Hydroxymethyl phosphonic acid ester, composition, polyurethane foam and product | ICL-IP美国有限公司 | 2017-11-24 | — | — | CN | disclosed |
| CN-104755487-B | Method for preparing hydroxymethylphosphonate, polyurethane foam-forming composition prepared thereby, polyurethane foam and article | ICL-IP美国有限公司 | 2017-09-19 | — | — | CN | disclosed |
| US-9657151-B1 | Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom | ICL-IP AMERICA INC. (US) | 2017-05-23 | — | — | US | disclosed |
| US-20170137590-A1 | METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM | ICL-IP America Inc (US) | 2017-05-18 | — | — | US | disclosed |
| US-9593220-B2 | Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom | ICL-IP AMERICA INC. (US) | 2017-03-14 | — | — | US | disclosed |
| US-20160347921-A1 | METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM | ICL-IP AMERICA INC. | 2016-12-01 | — | — | US | disclosed |
| EP-2376507-B1 | METHOD OF MAKING HYDROXYMETHYLPHOSPHONATES | ICL IP AMERICA INC (US) | 2013-05-15 | — | — | EP | disclosed |
| US-8198341-B2 | Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom | ICL-IP AMERICA INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-20110257287-A1 | Method of Making Hydroxymethylphosphonate, Polyurethane Foam-Forming Compositions, Polyurethane Foam and Articles Made Therefrom | STOWELL JEFFREY K | 2011-10-20 | — | — | US | disclosed |
| EP-2376507-A1 | METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS POLYURETHANE FOAM AND ARTICLES MADE THEREFORM | ICL-IP America Inc. (US) | 2011-10-19 | — | — | EP | disclosed |
| US-8008384-B2 | Liquid butylaryl phosphite compositions | CHEMTURA CORPORATION (US) | 2011-08-30 | — | — | US | disclosed |
| WO-2011014212-A1 | LIQUID BUTYLARYL PHOSPHITE COMPOSITIONS | CHEMTURA CORPORATION (US) | 2011-02-03 | — | — | WO | disclosed |
| US-20100190900-A1 | LIQUID BUTYLARYL PHOSPHITE COMPOSITIONS | CHEMTURA CORPORATION (US) | 2010-07-29 | — | — | US | disclosed |
| WO-2010080425-A1 | METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS POLYURETHANE FOAM AND ARTICLES MADE THEREFORM | SUPRESTA LLC. (US) | 2010-07-15 | — | — | WO | disclosed |
| US-20100160468-A1 | Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom | ICL-IP AMERICA INC. | 2010-06-24 | — | — | US | disclosed |
| US-20100076131-A1 | LIQUID BUTYLARYL PHOSPHITE COMPOSITIONS AND ALKYLATE COMPOSITIONS FOR MANUFACTURING SAME | CHEMTURA CORPORATION (US) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257287-A1 | Method of Making Hydroxymethylphosphonate, Polyurethane Foam-Forming Compositions, Polyurethane Foam and Articles Made Therefrom | PFAS, PGM2, NEFM | CA12 2013/4885CA1 1012/4885CA2 1625/4885 |
| US-20160347921-A1 | METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM | PFAS, PFKFB2, PFKFB1 | CA12 2361/4885CA1 1237/4885CA2 2128/4885 |
| US-20100160468-A1 | Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom | PFAS, PGM2, NEFM | CA12 2013/4885CA1 1012/4885CA2 1625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.