Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 7/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 7/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 7/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11603037 | 0.89 | CRHBP (0.43) | CRHBPCRHR2KEAP1NFE2L2CYP2C19 | |
| SCHEMBL11603107 | 0.81 | GABRP (0.37) | CYP1A2CYP3A4KDM4EALDH1A1POLB | |
| SCHEMBL11601677 | 0.81 | LMNA (0.35) | CRHBPCRHR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL6674577 | 0.78 | CRHBP (0.54) | CRHBPCRHR2KEAP1NFE2L2CYP2C19 | |
| SCHEMBL10612622 | 0.78 | CRHBP (0.54) | CRHBPCRHR2KEAP1NFE2L2CYP2C19 | |
| SCHEMBL11331634 | 0.73 | CRHBP (0.49) | CRHBPCRHR2KEAP1NFE2L2KDM4E | |
| SCHEMBL11602714 | 0.70 | MAT2A (0.46) | CRHBPCRHR2KEAP1NFE2L2CYP2C19 | |
| SCHEMBL29216871 | 0.68 | CRHBP (0.45) | CRHBPCRHR2KEAP1NFE2L2KDM4E | |
| SCHEMBL6833397 | 0.68 | CRHBP (0.43) | CRHBPCRHR2KEAP1NFE2L2POLB | |
| SCHEMBL15010394 | 0.67 | CRHBP (1.00) | CRHBPCRHR2KEAP1NFE2L2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4067981-A | FUNGICIDES, BACTERICIDES, INSECTICIDES, ACARICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1978-01-10 | — | — | US | disclosed |