Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.37 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.37 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756898 | 0.85 | PRKCI (0.53) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL10720 | 0.81 | IMPDH2 (0.47) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL1401379 | 0.81 | MAPT (0.42) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| Hydrochloric Acid SCHEMBL3671410 | 0.79 | IMPDH2 (0.46) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL16150680 | 0.75 | GABRA1 (0.38) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL22076879 | 0.74 | MAPT (0.47) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL6008269 | 0.73 | MAPT (0.50) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| Trifluoroacetic Acid SCHEMBL14638489 | 0.72 | PIN1 (0.42) | MAPTKDM4EALDH1A1HPGDHTT | |
| SCHEMBL5405534 | 0.69 | MAPT (0.47) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL15413217 | 0.69 | PARP1 (0.56) | MAPTKDM4EALDH1A1TDP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108864048-A | A kind of preparation method of dabigatran etexilate methanesulfonate | 天方药业有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-108864047-A | A kind of preparation method of non-peptide batroxobin inhibitor dabigatran etcxilate | 河南师范大学 | 2018-11-23 | — | — | CN | claimed |
| EP-1236712-B1 | AMIDINOPHENYLPYRUVIC ACID DERIVATIVE | AJINOMOTO KK (JP) | 2008-08-06 | — | — | EP | claimed |
| US-6710056-B2 | PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVE AN EXCELLENT ANTAGONISTIC EFFECT AGAINST ACTIVATED BLOOD COAGULATION FACTOR VII. | AJINOMOTO CO., INC. (JP) | 2004-03-23 | — | — | US | claimed |
| US-20030109547-A1 | Amidinophenylpyruvic acid derivatives | AJINOMOTO CO. INC (JP) | 2003-06-12 | — | — | US | claimed |
| EP-1236712-A1 | AMIDINOPHENYLPYRUVIC ACID DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2002-09-04 | — | — | EP | claimed |
| CN-109836412-A | A kind of preparation method of dabigatran etexilate methanesulfonate | 辽宁博美医药科技有限公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-108864048-A | A kind of preparation method of dabigatran etexilate methanesulfonate | 天方药业有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108864047-A | A kind of preparation method of non-peptide batroxobin inhibitor dabigatran etcxilate | 河南师范大学 | 2018-11-23 | — | — | CN | disclosed |
| CN-108864048-A | A kind of preparation method of dabigatran etexilate methanesulfonate | 天方药业有限公司 | 2018-11-23 | — | — | CN | disclosed |
| US-9868108-B2 | Specific sorbent for binding proteins and peptides, and separation method using the same | INSTRACTION GMBH (DE) | 2018-01-16 | — | — | US | disclosed |
| EP-2257297-B1 | COMPOUNDS FOR USE IN THE TREATMENT OF ACNE, SEBORRHOEA AND SEBHORROEIC DERMATITIS, OR FOR REDUCING SEBUM SECRETION | MIMETICA PTY LTD (AU) | 2017-10-18 | — | — | EP | disclosed |
| US-20170106349-A1 | SPECIFIC SORBENT FOR BINDING PROTEINS AND PEPTIDES, AND SEPARATION METHOD USING THE SAME | INSTRACTION GMBH (DE) | 2017-04-20 | — | — | US | disclosed |
| US-6589915-B1 | The invention relates to cyclohexenone derivatives of benzo-condensed, unsaturated 5-ring nitrogen heterocycles of general formula (I) wherein X represents N or a group C-R3, Y represents O, S, SO, SO2 or NR4 or X-Y represent S | BASF AKTIENGESELLSCHAFT (DE) | 2003-07-08 | — | — | US | disclosed |
| US-20030109547-A1 | Amidinophenylpyruvic acid derivatives | AJINOMOTO CO. INC (JP) | 2003-06-12 | — | — | US | disclosed |
| US-6541423-B1 | Controlling vegatation | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-01 | — | — | US | disclosed |
| EP-1236712-A1 | AMIDINOPHENYLPYRUVIC ACID DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6043226-A | TREATING BACTERIAL, PARASITIC AND PROTOZOAL INFECTIONS | PFIZER INC. (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0846127-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | Novartis AG (CH) | 1998-06-10 | — | — | EP | disclosed |
| WO-1997008193-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109547-A1 | Amidinophenylpyruvic acid derivatives | HABP2, F2, F7 | MAPT 4059/4885KDM4E 2614/4885ALDH1A1 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.