Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 4/20 | 0.35 |
| ▸ | ARG2 | P78540 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.32 |
| ▸ | GRM8 | O00222 | 2/20 | 0.32 |
| ▸ | GRM6 | O15303 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537184 | 0.75 | MEN1 (0.40) | ARG1ARG2TSHR | |
| SCHEMBL11600438 | 0.74 | ARG1 (0.34) | ARG1ARG2GRM2GRM3GRM8 | |
| SCHEMBL26332225 | 0.73 | SLC6A4 (0.47) | ARG1ARG2GRM2GRM3GRM8 | |
| SCHEMBL4835740 | 0.73 | SLC6A4 (0.47) | ARG1ARG2GRM2GRM3GRM8 | |
| SCHEMBL4835859 | 0.73 | SLC6A4 (0.47) | ARG1ARG2GRM2GRM3GRM8 | |
| SCHEMBL6380145 | 0.72 | FKBP1A (0.47) | CYP2C19TSHR | |
| SCHEMBL2524446 | 0.72 | ARG1 (0.34) | ARG1ARG2GRM2GRM3GRM8 | |
| SCHEMBL9729224 | 0.71 | ARG1 (0.33) | ARG1ARG2GRM2GRM3GRM8 | |
| SCHEMBL3704762 | 0.70 | ARG1 (0.39) | ARG1ARG2GRM2GRM3GRM8 | |
| SCHEMBL18828224 | 0.69 | ALDH1A1 (0.38) | CYP1A2TDP1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4111933-A | PROTECTION OF FUNCTIONAL GROUPS DURING REACTION AND THEIR SUBSEQUENT RESTORATION | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-05 | — | — | US | disclosed |