SCHEMBL11603045

SCHEMBL11603045

O=C(NC1(C(=O)O)CCCCC1)OCCBr

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CTSL P07711 4/20 0.38
CTSS P25774 4/20 0.38
CTSB P07858 2/20 0.38
FAAH O00519 6/20 0.35
TRPV1 Q8NER1 6/20 0.34
CNR2 P34972 2/20 0.34
SLC18A2 Q05940 2/20 0.33
CTSK P43235 3/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP2C19 P33261 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4053495 0.81 KMT2A (0.41) CTSLCTSSCTSBCNR2ALDH1A1
SCHEMBL526390 0.81 KMT2A (0.41) CTSLCTSSCTSBCNR2ALDH1A1
SCHEMBL1536750 0.79 KMT2A (0.42) CNR2ALDH1A1
SCHEMBL9551099 0.77 CTSB (0.40) CTSLCTSSCTSBFAAHTRPV1
SCHEMBL11600433 0.76 CTSS (0.41) CTSLCTSSCTSBFAAHTRPV1
SCHEMBL11602809 0.75 CTSL (0.37) CTSLCTSSCTSBFAAHTRPV1
SCHEMBL5674430 0.75 SLC18A2 (0.42) CTSLCTSSCTSBFAAHCNR2
SCHEMBL19640034 0.75 EPHX1 (0.42) ALDH1A1
SCHEMBL7100758 0.74 MAPT (0.41) CTSLCTSSCTSBFAAHTRPV1
SCHEMBL12869613 0.74 CTSL (0.36) CTSLCTSSCTSBFAAHCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4111933-A PROTECTION OF FUNCTIONAL GROUPS DURING REACTION AND THEIR SUBSEQUENT RESTORATION BAYER AKTIENGESELLSCHAFT (DE) 1978-09-05 US disclosed