Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Levulinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levulinic Acid SCHEMBL28938456 | 0.97 | ALDH1A1 (0.59) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Levulinic Acid SCHEMBL377115 | 0.97 | ALDH1A1 (0.59) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Levulinic Acid SCHEMBL1683269 | 0.97 | ALDH1A1 (0.59) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Levulinic Acid SCHEMBL21815796 | 0.94 | ALDH1A1 (0.62) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Levulinic Acid SCHEMBL21815731 | 0.94 | ALDH1A1 (0.62) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Levulinic Acid SCHEMBL25222492 | 0.94 | ALDH1A1 (0.62) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Levulinic Acid SCHEMBL21815652 | 0.94 | ALDH1A1 (0.62) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Levulinic Acid SCHEMBL21815632 | 0.94 | ALDH1A1 (0.62) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Levulinic Acid SCHEMBL11315082 | 0.94 | — | — | |
| Levulinic Acid SCHEMBL439418 | 0.94 | ALDH1A1 (0.62) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5365 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260091072-A1 | FOOD PRODUCTS COMPRISING OXALIC ACID- OR OXALATE-FREE INONOTUS OBLIQUUS EXTRACT | THE BETTER FOR YOU COMPANY, LLC (US) | 2026-04-02 | — | — | US | claimed |
| CN-116942918-A | Self-solidifying composite bone implant based on human body essential amino acid and preparation method thereof | 中鼎凯瑞科技成都有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-114479952-B | Biomass hydrogen production heat carrier and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-07-28 | — | — | CN | claimed |
| WO-2023091607-A1 | OXALIC ACID OR OXALATE FREE INONOTUS OBLIQUUS EXTRACT AND USES THEREOF | THE BETTER FOR YOU COMPANY, LLC (US) | 2023-05-25 | — | — | WO | claimed |
| CN-115868517-A | Citric acid calcium malate pancake and making method thereof | 九品贡(山东)食品有限公司 | 2023-03-31 | — | — | CN | claimed |
| US-11534458-B2 | Phosphorus-sparing nutritional composition | ALBION LABORATORIES, INC. (US) | 2022-12-27 | — | — | US | claimed |
| CN-112194737-B | Comprehensive utilization method of surplus procambarus clarkii waste with high added value | 中国水产科学研究院长江水产研究所 | 2022-09-27 | — | — | CN | claimed |
| CN-114479952-A | Biomass hydrogen production heat carrier and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114403452-A | Preparation method and application of calcium levulinate composite additive | 宁乡新阳化工有限公司 | 2022-04-29 | — | — | CN | claimed |
| US-20210368840-A1 | PROCESS TO PREPARE SODIUM AND/OR POTASSIUM SALT PRODUCTS, SALT PRODUCT OBTAINABLE THEREBY AND THE USE THEREOF | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2021-12-02 | — | — | US | claimed |
| EP-0263224-A2 | Chewing gum mineral supplement | WARNER-LAMBERT COMPANY (US) | 1988-04-13 | — | — | EP | claimed |
| US-4678661-A | Effervescent composition and method of making same | GERHARD GERGELY, GARTENGASSE 8, A1050 WEIN, AUSTRIA | 1987-07-07 | — | — | US | claimed |
| EP-0208362-A1 | Dietary supplements containing iron and enterically coated calcium | THE PROCTER & GAMBLE COMPANY (US) | 1987-01-14 | — | — | EP | claimed |
| EP-0192367-A2 | Chewable mineral supplement | WARNER-LAMBERT COMPANY (US) | 1986-08-27 | — | — | EP | claimed |
| US-4582709-A | EDIBLE POLYOL AND MINERALS MIXED INTO SOFT CANDY BASE | WARNER-LAMBERT COMPANY (US) | 1986-04-15 | — | — | US | claimed |
| US-4274427-A | SALT FILLERS RETAIN THE EXPANDED BULK | PHILIP MORRIS INCORPORATED (US) | 1981-06-23 | — | — | US | claimed |
| US-4252797-A | ANTIINFLAMMATORY AGENTS | ROSENTHAL WALTER | 1981-02-24 | — | — | US | claimed |
| US-4185093-A | Preparation and method for treatment of hypocalcemia, hypophosphatemia and downer cow syndrome in animals | CARNES ALLEN R | 1980-01-22 | — | — | US | claimed |
| US-4013784-A | DELAYED RELEASE PHARMACEUTICAL PREPARATIONS | SPEISER PETER | 1977-03-22 | — | — | US | claimed |
| US-4001409-A | ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1977-01-04 | — | — | US | claimed |