Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Levulinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levulinic Acid SCHEMBL116039 | 0.97 | ALDH1A1 (0.62) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Levulinic Acid SCHEMBL406977 | 0.97 | — | — | |
| Levulinic Acid SCHEMBL1683269 | 0.94 | ALDH1A1 (0.59) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Levulinic Acid SCHEMBL30439842 | 0.94 | ALDH1A1 (0.59) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Levulinic Acid SCHEMBL377115 | 0.94 | ALDH1A1 (0.59) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Levulinic Acid SCHEMBL25222492 | 0.91 | ALDH1A1 (0.62) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Levulinic Acid SCHEMBL21815632 | 0.91 | ALDH1A1 (0.62) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Levulinic Acid SCHEMBL10791493 | 0.91 | ALDH1A1 (0.62) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Levulinic Acid SCHEMBL21815731 | 0.91 | ALDH1A1 (0.62) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Levulinic Acid SCHEMBL21815796 | 0.91 | ALDH1A1 (0.62) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114356002-A | Intelligent building environment-friendly control system | 河南省第五建设集团有限公司 | 2022-04-15 | — | — | CN | disclosed |