(Phenylsulfonyl)Benzene

(Phenylsulfonyl)Benzene

SCHEMBL11604384

CCOC(=O)Cl.O=S(=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.50
CHRM2 P08172 1/20 0.49
CHRM1 P11229 1/20 0.49
TUBB4A P04350 1/20 0.49
TUBB P07437 1/20 0.49
TUBA3C P0DPH7 1/20 0.49
TUBA1B P68363 1/20 0.49
TUBA4A P68366 1/20 0.49
TUBB4B P68371 1/20 0.49
TUBB3 Q13509 1/20 0.49
TUBB2A Q13885 1/20 0.49
TUBB8 Q3ZCM7 1/20 0.49
TUBA3E Q6PEY2 1/20 0.49
TUBA1A Q71U36 1/20 0.49
TUBA1C Q9BQE3 1/20 0.49
TUBB6 Q9BUF5 1/20 0.49
TUBB2B Q9BVA1 1/20 0.49
TUBB1 Q9H4B7 1/20 0.49
ATM Q13315 1/20 0.49
GAA P10253 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Phenylsulfonyl)Benzene SCHEMBL19970437 0.82 ALOX15 (0.54) HTR6CHRM2CHRM1TUBB4ATUBB
SCHEMBL27584145 0.81 ALDH1A1 (0.55) ATMGAAALDH1A1KMT2AHSD11B1
SCHEMBL28541685 0.79 CA12 (0.60) GAAL3MBTL1ALDH1A1KMT2ALMNA
SCHEMBL5664532 0.77 HSD11B1 (0.45) HTR6L3MBTL1ALDH1A1HSD11B1LMNA
(Phenylsulfonyl)Benzene SCHEMBL1679634 0.77 HTR6 (0.64) HTR6CHRM2CHRM1L3MBTL1ALDH1A1
(Phenylsulfonyl)Benzene SCHEMBL8778772 0.76 HTR6 (0.70) HTR6GAAL3MBTL1ALDH1A1TSHR
(Phenylsulfonyl)Benzene SCHEMBL9642349 0.76 HTR6 (0.78) HTR6GAAL3MBTL1NPSR1ALDH1A1
Benzamide SCHEMBL27276187 0.75 MAPT (0.57) L3MBTL1ALDH1A1KMT2ATSHRLMNA
Phenylacetic Acid SCHEMBL27683641 0.75 AKR1B1 (0.61) GAAL3MBTL1ALDH1A1KMT2ATSHR
SCHEMBL6024157 0.74 ALDH1A1 (0.54) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4124393-A PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1978-11-07 US disclosed