Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 5/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1160635 | 0.85 | APEX1 (0.44) | PTGDR2HRH3ALOX5KDM4EALDH1A1 | |
| SCHEMBL13041575 | 0.74 | PTGDR2 (0.43) | PTGDR2HRH3ALOX5KDM4EALDH1A1 | |
| SCHEMBL1160432 | 0.73 | PTGDR2 (0.38) | PTGDR2HRH3ALOX5KDM4EALDH1A1 | |
| SCHEMBL13078148 | 0.72 | PTGDR2 (0.42) | PTGDR2HRH3ALOX5KDM4EALDH1A1 | |
| SCHEMBL1160757 | 0.72 | PTGDR2 (0.38) | PTGDR2HRH3ALOX5KDM4EALDH1A1 | |
| SCHEMBL12119027 | 0.70 | HSD17B1 (0.38) | — | |
| SCHEMBL1160395 | 0.70 | L3MBTL1 (0.37) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL1160333 | 0.69 | HRH3 (0.44) | PTGDR2HRH3ALOX5KDM4EALDH1A1 | |
| SCHEMBL13710179 | 0.68 | PTGDR2 (0.46) | PTGDR2ALOX5KDM4EALDH1A1CYP1A2 | |
| SCHEMBL8005690 | 0.68 | PTGDR2 (0.68) | PTGDR2ALOX5KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459547-B1 | HERBICIDALLY ACTIVE HETEROARYL-SUBSTITUTED CYCLIC DIONES OR DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2016-04-20 | — | — | EP | disclosed |
| US-9051300-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2015-06-09 | — | — | US | disclosed |
| US-20120202691-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-08-09 | — | — | US | disclosed |
| EP-2459547-A1 | HERBICIDALLY ACTIVE HETEROARYL-SUBSTITUTED CYCLIC DIONES OR DERIVATIVES THEREOF | Syngenta Limited (GB) | 2012-06-06 | — | — | EP | disclosed |
| WO-2011012862-A1 | HERBICIDALLY ACTIVE HETEROARYL-SΥBSTITΥTED CYCLIC DIONES OR DERIVATIVES THEREOF | SYNGENTA LIMITED (GB) | 2011-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202691-A1 | NOVEL HERBICIDES | DDT, HCN1, HDHD5 | PTGDR2 2952/4885HRH3 905/4885ALOX5 657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.