Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.68 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.59 |
| ▸ | ATP4A | P20648 | 2/20 | 0.55 |
| ▸ | ATP4B | P51164 | 2/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23424392 | 0.84 | PTGDR2 (0.52) | PTGDR2ALOX5KDM4E | |
| SCHEMBL20767251 | 0.83 | ALDH1A1 (0.67) | PTGDR2PRMT1KDM4ENPC1PKM | |
| SCHEMBL718120 | 0.80 | PTGDR2 (0.54) | PTGDR2ATP4AATP4BKDM4ENPC1 | |
| SCHEMBL11466220 | 0.80 | ALDH1A1 (0.67) | PTGDR2ATP4AATP4BKDM4ECYP1A2 | |
| SCHEMBL11455410 | 0.80 | PTGS2 (0.66) | PTGDR2ALOX5KDM4ENPC1PKM | |
| SCHEMBL18003932 | 0.79 | PTGDR2 (0.51) | PTGDR2PRMT1ALOX5KDM4ENPC1 | |
| SCHEMBL31303783 | 0.79 | PRMT1 (0.67) | PTGDR2PRMT1ALOX5KDM4ENPC1 | |
| SCHEMBL18005062 | 0.79 | PTGDR2 (0.46) | PTGDR2PRMT1ATP4AATP4BALOX5 | |
| SCHEMBL18003676 | 0.77 | L3MBTL1 (0.76) | PTGDR2ALOX5KDM4ENPC1PKM | |
| SCHEMBL10662994 | 0.77 | ATP4A (0.73) | PTGDR2ATP4AATP4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000019994-A9 | ESTROGEN RECEPTOR LIGANDS | UNIV ILLINOIS (US) | 2000-08-31 | — | — | WO | disclosed |
| WO-2000019994-A1 | ESTROGEN RECEPTOR LIGANDS | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2000-04-13 | — | — | WO | disclosed |