Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.54 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31681757 | 0.99 | NOD2 (0.55) | NOD2NOD1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL31681753 | 0.92 | MAPT (0.54) | NOD2NOD1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL23854160 | 0.91 | NOD2 (0.44) | NOD2NOD1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL23852569 | 0.91 | MAPT (0.53) | NOD2NOD1ALDH1A1KDM4ETP53 | |
| SCHEMBL23853369 | 0.91 | NOD2 (0.44) | NOD2NOD1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6115173 | 0.91 | TSHR (0.52) | NOD2NOD1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL18250041 | 0.91 | MAPT (0.52) | NOD2NOD1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6115574 | 0.90 | MEN1 (0.45) | NOD2NOD1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL23853955 | 0.89 | NOD2 (0.42) | NOD2NOD1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL31681758 | 0.89 | NOD2 (0.42) | NOD2NOD1ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12410164-B2 | Heterocyclic compounds and medical use thereof | FONDAZIONE TELETHON (IT) | 2025-09-09 | — | — | US | disclosed |
| US-20120129884-A1 | PHOTOCHEMOTHERAPEUTIC HETEROCYCLIC AGENTS HAVING ANTIPROLIFERATIVE AND ANTINEOPLASTIC ACTIVITY | UNIVERSITA DEGLI STUDI DI PADOVA (IT) | 2012-05-24 | — | — | US | disclosed |
| WO-2011013159-A1 | PHOTOCHEMOTHERAPEUTIC HETEROCYCLIC AGENTS HAVING ANTIPROLIFERATIVE AND ANTINEOPLASTIC ACTIVITY | UNIVERSITÀ DEGLI STUDI DI PADOVA (IT) | 2011-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12410164-B2 | Heterocyclic compounds and medical use thereof | NPPA, NPR1, CYC1 | NOD2 183/4885NOD1 400/4885ALDH1A1 2994/4885 |
| US-20120129884-A1 | PHOTOCHEMOTHERAPEUTIC HETEROCYCLIC AGENTS HAVING ANTIPROLIFERATIVE AND ANTINEOPLASTIC ACTIVITY | PCNA, ERCC4, UBQLN2 | NOD2 2895/4885NOD1 4016/4885ALDH1A1 748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.