Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1160587 | 0.91 | NOD2 (0.54) | NOD2NOD1MAPTTDP1KDM4E | |
| SCHEMBL31681753 | 0.90 | MAPT (0.54) | NOD2NOD1PDE3BPDE3AMAPT | |
| SCHEMBL31681757 | 0.90 | NOD2 (0.55) | NOD2NOD1MAPTTDP1KDM4E | |
| SCHEMBL23854160 | 0.89 | NOD2 (0.44) | NOD2NOD1MAPTTDP1KDM4E | |
| SCHEMBL23852569 | 0.89 | MAPT (0.53) | NOD2NOD1PDE3BPDE3AMAPT | |
| SCHEMBL6115173 | 0.89 | TSHR (0.52) | NOD2NOD1MAPTTDP1KDM4E | |
| SCHEMBL18250041 | 0.89 | MAPT (0.52) | NOD2NOD1MAPTTDP1KDM4E | |
| SCHEMBL6115574 | 0.88 | MEN1 (0.45) | NOD2NOD1MAPTTDP1KDM4E | |
| SCHEMBL23853955 | 0.87 | NOD2 (0.42) | NOD2NOD1MAPTTDP1KDM4E | |
| SCHEMBL18250050 | 0.87 | MEN1 (0.46) | NOD2NOD1MAPTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12410164-B2 | Heterocyclic compounds and medical use thereof | FONDAZIONE TELETHON (IT) | 2025-09-09 | — | — | US | disclosed |
| EP-3883931-A1 | HETEROCYCLIC COMPOUNDS AND MEDICAL USE THEREOF | Fondazione Telethon (IT) | 2021-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12410164-B2 | Heterocyclic compounds and medical use thereof | NPPA, NPR1, CYC1 | NOD2 183/4885NOD1 400/4885PDE3B 306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.