Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.51 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6115173 | 0.98 | TSHR (0.52) | MAPTTSHRALDH1A1POLBTDP1 | |
| SCHEMBL31681757 | 0.92 | NOD2 (0.55) | MAPTTSHRALDH1A1POLBTDP1 | |
| SCHEMBL1160587 | 0.91 | NOD2 (0.54) | MAPTTSHRALDH1A1POLBTDP1 | |
| SCHEMBL31681753 | 0.90 | MAPT (0.54) | MAPTTSHRALDH1A1POLBTDP1 | |
| SCHEMBL23854160 | 0.89 | NOD2 (0.44) | MAPTTSHRALDH1A1POLBTDP1 | |
| SCHEMBL23853369 | 0.89 | NOD2 (0.44) | MAPTTSHRALDH1A1POLBTDP1 | |
| SCHEMBL23852569 | 0.89 | MAPT (0.53) | MAPTTSHRALDH1A1POLBTDP1 | |
| SCHEMBL18250050 | 0.89 | MEN1 (0.46) | MAPTTSHRALDH1A1POLBTDP1 | |
| SCHEMBL23853822 | 0.88 | ALDH1A1 (0.47) | MAPTTSHRALDH1A1POLBTDP1 | |
| SCHEMBL31681751 | 0.88 | ALDH1A1 (0.47) | MAPTTSHRALDH1A1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016185348-A1 | 4,5,6,9-TETRAHYDROPYRROLO[2',3':3,4]CYCLOHEPTA[1,2-D] ISOXAZOLE, PROCESS FOR THEIR PRODUCTION AND THEIR USES AS ANTITUMOR AGENTS | UNIVERSITA' DEGLI STUDI DI PALERMO (IT) | 2016-11-24 | — | — | WO | disclosed |
| WO-2016185348-A1 | 4,5,6,9-TETRAHYDROPYRROLO[2',3':3,4]CYCLOHEPTA[1,2-D] ISOXAZOLE, PROCESS FOR THEIR PRODUCTION AND THEIR USES AS ANTITUMOR AGENTS | UNIVERSITA' DEGLI STUDI DI PALERMO (IT) | 2016-11-24 | — | — | WO | disclosed |