Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 6/20 | 0.48 |
| ▸ | CA12 | O43570 | 5/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | ILK | Q13418 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11605260 | 0.87 | KMT2A (0.58) | PKMKMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11603253 | 0.80 | PPARA (0.50) | PKMKMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11601837 | 0.76 | PPARA (0.45) | PKMKMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11604954 | 0.76 | SMN1; SMN2 (0.50) | PKMKMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11602024 | 0.76 | ALDH1A1 (0.56) | PKMKMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11606470 | 0.75 | SMN1; SMN2 (0.41) | PKMKMT2AMAPTNPC1MAPK1 | |
| SCHEMBL687982 | 0.72 | ALDH1A1 (0.78) | PKMKMT2AMAPTCA2CA12 | |
| SCHEMBL11604251 | 0.72 | MAPT (0.50) | PKMKMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11601529 | 0.71 | SMN1; SMN2 (0.57) | KMT2AMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11605659 | 0.71 | DYRK1A (0.43) | PKMKMT2AMAPTNPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096111-A | (BENZOTHIAZOLYL-THIO)-SUBSTITUTED ANTHRAQUINONES | BAYER AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |