Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFB | P00751 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 13/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 11/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 10/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 9/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11450988 | 0.89 | TAAR1 (0.66) | CFBTAAR1ADRA2AADRA2CADRA2B | |
| SCHEMBL11440748 | 0.79 | TAAR1 (0.75) | CFBTAAR1ADRA2AADRA2CADRA2B | |
| SCHEMBL4266232 | 0.75 | HPGD (0.55) | CFBTAAR1LMNAMEN1KMT2A | |
| SCHEMBL7629026 | 0.73 | ADRA2A (0.50) | CFBTAAR1ADRA2AADRA2CADRA2B | |
| SCHEMBL11379517 | 0.73 | CFB (0.47) | CFBTAAR1ADRA2AADRA2CADRA2B | |
| SCHEMBL1852745 | 0.72 | CFB (0.49) | CFBTAAR1ADRA2AADRA2CADRA2B | |
| SCHEMBL1178307 | 0.71 | CYP2A13 (0.43) | CFBCYP2D6CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL11185255 | 0.70 | PTGS2 (0.47) | ADRA2AADRA2CADRA2BADRA1AADRA1D | |
| SCHEMBL7048730 | 0.70 | TAAR1 (0.60) | CFBTAAR1ADRA2AADRA2CADRA2B | |
| SCHEMBL1178958 | 0.70 | GAA (0.46) | CFBCYP2D6CYP2C9MEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4094964-A | IMMUNOASSAY, HAPTEN, ANTIGEN | HOFFMANN-LA ROCHE INC. (US) | 1978-06-13 | — | — | US | disclosed |