Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | TDP2 | O95551 | 1/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | GALK1 | P51570 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.55 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728170 | 0.90 | ADRB2 (0.54) | FAAHKMT2AALDH1A1MEN1HTT | |
| SCHEMBL5608105 | 0.79 | FAAH (0.57) | FAAHKMT2AALDH1A1MEN1HTT | |
| SCHEMBL12987195 | 0.78 | FAAH (0.51) | FAAHKMT2AALDH1A1MEN1HTT | |
| SCHEMBL1740329 | 0.78 | CTSL (0.53) | FAAHKMT2AALDH1A1MEN1HTT | |
| SCHEMBL28793250 | 0.76 | CXCR3 (0.51) | FAAHKMT2AALDH1A1MEN1HTT | |
| SCHEMBL13804119 | 0.75 | CTSL (0.52) | FAAHKMT2AALDH1A1MEN1HTT | |
| SCHEMBL9698835 | 0.75 | ADRB2 (0.54) | FAAHKMT2AALDH1A1MEN1HTT | |
| SCHEMBL10604536 | 0.75 | CTSL (0.49) | FAAHKMT2AALDH1A1MEN1HTT | |
| SCHEMBL29120775 | 0.75 | LMNA (0.53) | FAAHKMT2AALDH1A1MEN1HTT | |
| SCHEMBL17133523 | 0.74 | FAAH (0.53) | FAAHKMT2AALDH1A1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076840-A | TREATMENT OF ALCOHOLISM | ASTRA LAKEMEDEL AKTIEBOLAG (SW) | 1978-02-28 | — | — | US | disclosed |