Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.57 |
| ▸ | NPC1 | O15118 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SCD | O00767 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29176359 | 0.77 | RAB9A (0.60) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29904457 | 0.74 | HSPA5 (0.71) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8558332 | 0.74 | HSPA5 (0.71) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3206087 | 0.72 | RAB9A (0.66) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7946681 | 0.71 | RAB9A (0.56) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2656771 | 0.71 | RAB9A (0.68) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL995829 | 0.69 | NPC1 (1.00) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2628996 | 0.69 | NPC1 (0.76) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11606613 | 0.69 | DAO (0.53) | MEN1KMT2APOLB | |
| SCHEMBL4290771 | 0.68 | NPC1 (0.79) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183818-A1 | ANTIBIOTIC SUSCEPTIBILITY OF MICROORGANISMS AND RELATED MARKERS, COMPOSITIONS, METHODS AND SYSTEMS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2023-06-15 | — | — | US | disclosed |
| WO-2020028718-A1 | ANTIBIOTIC SUSCEPTIBILITY OF MICROORGANISMS AND RELATED MARKERS, COMPOSITIONS, METHODS AND SYSTEMS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-02-06 | — | — | WO | disclosed |
| US-4084051-A | BACTERICIDES, HERBICIDES | STERLING DRUG INC. (US) | 1978-04-11 | — | — | US | disclosed |
| US-4046775-A | 4,5-Dihalopyrrole-2-carboxamides | STERLING DRUG INC. (US) | 1977-09-06 | — | — | US | disclosed |
| US-3963480-A | Herbicidal pyrrole-2-carboxamides | STERLING DRUG INC. (US) | 1976-06-15 | — | — | US | disclosed |